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Phase

Phase 1/2 1Phase 1 1

Status

Unknown 2Recruiting 2

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2

Conditions

Sarcoma 163Osteosarcoma 56Gastrointestinal Stromal Tumors 40Bone Neoplasms 32Glioblastoma 22Gliosarcoma 21Sarcoma, Ewing 20Dendritic Cell Sarcoma, Interdigitating 20Lymphoma 19Brain Neoplasms 18Neoplasms 17Central Nervous System Neoplasms 17Stomach Neoplasms 16Breast Neoplasms 16Ovarian Neoplasms 15Leiomyosarcoma 15Rhabdomyosarcoma 13Neuroblastoma 13Neoplasm Metastasis 13Recurrence 12Precursor Cell Lymphoblastic Leukemia-Lymphoma 12Pancreatic Neoplasms 12Liposarcoma 12Astrocytoma 12Esophageal Neoplasms 11Chondrosarcoma 11Burkitt Lymphoma 11Sarcoma, Synovial 10Oligodendroglioma 9Neurofibrosarcoma 9

Interventions

seclidemstat 2Topotecan 2Cyclophosphamide 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Unknown × Myoepithelioma × Sarcoma × Clear all
NCT03600649 2023-11-21

Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related Sarcomas

Salarius Pharmaceuticals, LLC

Phase 1 Unknown
50 enrolled
Sarcoma

Histiocytoma, Angiomatoid Fibrous, Chondrosarcoma, Extraskeletal Myxoid, Fibroma, Myoepithelioma, Sarcoma, Sarcoma, Ewing, Liposarcoma, Myxoid, Sarcoma, Clear Cell, Desmoplastic Small Round Cell Tumor

NCT05266196 2023-08-01

A Rollover Protocol to Allow for Continued Access to the LSD1 Inhibitor Seclidemstat (SP-2577)

Salarius Pharmaceuticals, LLC

Phase 1/2 Unknown
10 enrolled
Sarcoma

Histiocytoma, Angiomatoid Fibrous, Chondrosarcoma, Extraskeletal Myxoid, Myoepithelioma, Sarcoma, Ewing, Liposarcoma, Myxoid, Sarcoma, Clear Cell, Desmoplastic Small Round Cell Tumor

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