Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Recruiting 2Active not recruiting 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 2Observational 1

Sponsor

Cancer Type

Sarcoma 3Plasma cell 1CNS 1

Conditions

Sarcoma 69Osteosarcoma 29Sarcoma, Ewing 20Rhabdomyosarcoma 17Ovarian Neoplasms 17Melanoma 17Neuroblastoma 15Gastrointestinal Stromal Tumors 15Colorectal Neoplasms 12Bone Neoplasms 12Wilms Tumor 11Sarcoma, Kaposi 11Rhabdoid Tumor 11Neoplasms 11Lymphoma, Non-Hodgkin 10Hepatoblastoma 10Glioma 10Breast Neoplasms 10Stomach Neoplasms 9Medulloblastoma 9Liposarcoma 9Ependymoma 9Neurofibrosarcoma 8Neuroectodermal Tumors, Primitive, Peripheral 8Neoplasm Metastasis 8Head and Neck Neoplasms 8Carcinoma, Non-Small-Cell Lung 8Carcinoma, Hepatocellular 8Prostatic Neoplasms 7Pancreatic Neoplasms 7

Interventions

tazemetostat 1selinexor 1pazopanib 1Proton Therapy 1Ifosfamide 1Doxorubicin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Nerve Sheath Neoplasms × Sarcoma × 30 days × Clear all
NCT04917042 2026-06-04

Tazemetostat in Malignant Peripheral Nerve Sheath Tumors

University of Florida

Phase 2 Active not recruiting
10 enrolled 12 charts
Sarcoma

Inhibition, Psychological, Sarcoma, Nerve Sheath Neoplasms, Neurofibrosarcoma

NCT06222203 2026-06-04

Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)

National Institutes of Health Clinical Center (CC)

Recruiting
225 enrolled
CNSSarcoma

Neurofibroma, Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform, Neurofibrosarcoma

NCT06239272 2026-05-19

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

St. Jude Children's Research Hospital

Phase 1/2 Recruiting
139 enrolled
Plasma cellSarcoma

Histiocytoma, Angiomatoid Fibrous, Chondrosarcoma, Extraskeletal Myxoid, Fibrosarcoma, Glomus Tumor, Granuloma, Plasma Cell, Hemangiosarcoma, Liposarcoma, Myoepithelioma, Sarcoma, Osteosarcoma, Disorders of Sex Development, Granular Cell Tumor, Neoplasms, Adipose Tissue, Liposarcoma, Myxoid, Dermatofibrosarcoma, Sarcoma, Clear Cell, Smooth Muscle Tumor, Nerve Sheath Neoplasms, Neurofibrosarcoma, Hemangioendothelioma, Epithelioid, Vascular Neoplasms, Solitary Fibrous Tumors

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