Announcements Trials
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Phase

Phase 1 1

Status

Recruiting 2Active not recruiting 1

Sponsor Class

NIH 3

Study Type

Observational 2Interventional 1

Sponsor

Cancer Type

CNS 17Sarcoma 3Other hematologic neoplasm 1Myeloid 1Lymphoid 1

Conditions

Sarcoma 189Osteosarcoma 72Sarcoma, Ewing 49Rhabdomyosarcoma 44Melanoma 40Neuroblastoma 35Gastrointestinal Stromal Tumors 34Neoplasms 32Colorectal Neoplasms 29Glioblastoma 28Bone Neoplasms 27Neoplasm Metastasis 26Ovarian Neoplasms 25Breast Neoplasms 25Wilms Tumor 22Gliosarcoma 22Glioma 22Rhabdoid Tumor 21Lymphoma, Non-Hodgkin 21Sarcoma, Kaposi 20Liposarcoma 20Carcinoma, Non-Small-Cell Lung 20Pancreatic Neoplasms 18Neurofibrosarcoma 18Medulloblastoma 18Hepatoblastoma 18Carcinoma, Renal Cell 18Lymphoma 17Thyroid Neoplasms 16Desmoid Tumors 16

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Neurofibroma, Plexiform × Sarcoma × 90 days × Clear all
NCT00924196 2026-06-04

Natural History Study of Patients With Neurofibromatosis Type I

National Institutes of Health Clinical Center (CC)

Active not recruiting
259 enrolled
CNSSarcoma

Neurofibroma, Neurofibromatosis 1, Neurofibroma, Plexiform, Neurofibrosarcoma, Optic Nerve Glioma

NCT06222203 2026-06-04

Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)

National Institutes of Health Clinical Center (CC)

Recruiting
225 enrolled
CNSSarcoma

Neurofibroma, Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform, Neurofibrosarcoma

NCT02390752 2026-06-01

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
54 enrolled
CNSLymphoidOther hematologic neoplasmSarcoma

Sarcoma, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute, Neurofibroma, Plexiform, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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