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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 2Sarcoma 1Other hematologic neoplasm 1Lymphoid 1Endocrine 1

Conditions

Vomiting 2Sarcoma 2Nausea 2Spinal Cord Neoplasms 1Rhabdoid Tumor 1Recurrence 1Prolactinoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pituitary Neoplasms 1Optic Nerve Glioma 1Oligodendroglioma 1Neoplasms 1Medulloblastoma 1Lymphoma, Large-Cell, Anaplastic 1Leukemia, Large Granular Lymphocytic 1Familial ependymoma 1Dendritic Cell Sarcoma, Interdigitating 1Choroid Plexus Neoplasms 1Burkitt Lymphoma 1Astrocytoma 1Adenoma, Chromophobe 1Adenoma, Basophil 1Adenoma, Acidophil 1

Interventions

Temozolomide 32Radiotherapy 11Magnetic Resonance Spectroscopy 11Carboplatin 10Bevacizumab 10Irinotecan 9Carmustine 9Filgrastim 8Erlotinib Hydrochloride 8Surgical Procedures, Operative 7sargramostim 5Imatinib Mesylate 52-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 52,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 5temsirolimus 4Vorinostat 4Sirolimus 4Procarbazine 4Peripheral Blood Stem Cell Transplantation 4O(6)-benzylguanine 4aldesleukin 3Thalidomide 3Iodine-125 3Immunohistochemistry 3Gadolinium DTPA 3Cyclophosphamide 3Bortezomib 3Biopsy 3lonafarnib 2imetelstat 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Oligodendroglioma × Calcium Dobesilate × Sarcoma × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

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