Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2Gynecologic 2Genitourinary 2Gastrointestinal 2CNS 2

Conditions

Gliosarcoma 131Glioblastoma 128Central Nervous System Neoplasms 58Glioma 51Brain Neoplasms 48Astrocytoma 45Oligodendroglioma 32Sarcoma 23Sarcoma, Ewing 22Rhabdomyosarcoma 18Neuroblastoma 14Medulloblastoma 14Ependymoma 14Osteosarcoma 10Neoplasms 6Choroid Plexus Neoplasms 6Wilms Tumor 5Recurrence 5Ovarian Neoplasms 5Neuroectodermal Tumors, Primitive, Peripheral 5Glioma, Subependymal 5Familial ependymoma 5Rhabdoid Tumor 4Pinealoma 4Optic Nerve Glioma 4Neuroectodermal Tumors, Primitive 4Leiomyosarcoma 4Diffuse Intrinsic Pontine Glioma 4Testicular Neoplasms 3Kidney Neoplasms 3

Interventions

Carboplatin 3Temozolomide 2Peripheral Blood Stem Cell Transplantation 2Filgrastim 2sodium thiosulfate 1ixabepilone 1etoposide phosphate 1Thiotepa 1Restraint, Physical 1Radiotherapy 1Psychiatric Rehabilitation 1PT-100 dipeptide 1Oxaliplatin 1O(6)-benzylguanine 1Microarray Analysis 1Melphalan 1Immunohistochemistry 1Ifosfamide 1Granulocyte Colony-Stimulating Factor 1Etoposide 1Electroacupuncture 1Dasatinib 1Cyproheptadine 1Cyclophosphamide 1Busulfan 1Bone Marrow Transplantation 1Blotting, Western 1Arsenic Trioxide 1Analgesia 1Amifostine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Ovarian Germ Cell Cancer × Temozolomide × Sarcoma × Clear all
NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00303940 2012-03-15

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
26 enrolled
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma

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