Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Terminated 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 10Gastrointestinal 5Head & Neck 4Dermatologic 4Other solid neoplasm 3Lymphoid 2Genitourinary 2Breast 2Sarcoma 1Gynecologic 1Endocrine 1

Conditions

Sarcoma 316Glioblastoma 176Gliosarcoma 166Astrocytoma 125Brain Neoplasms 117Osteosarcoma 101Glioma 97Central Nervous System Neoplasms 96Oligodendroglioma 92Neuroblastoma 88Neoplasms 87Melanoma 87Breast Neoplasms 81Ovarian Neoplasms 70Lymphoma 67Dendritic Cell Sarcoma, Interdigitating 64Sarcoma, Ewing 63Rhabdomyosarcoma 63Recurrence 63Carcinoma, Non-Small-Cell Lung 62Precursor Cell Lymphoblastic Leukemia-Lymphoma 59Burkitt Lymphoma 59Lymphoma, Non-Hodgkin 55Medulloblastoma 53Wilms Tumor 52Colorectal Neoplasms 52Pancreatic Neoplasms 51Neoplasm Metastasis 49Lymphoma, Large B-Cell, Diffuse 47Carcinoma, Hepatocellular 44

Interventions

spartalizumab 1ribociclib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Parkinson Disease 4, Autosomal Dominant Lewy Body × Sarcoma × Clear all
NCT04000529 2025-09-30

Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies

Novartis

Phase 1 Terminated
122 enrolled
GastrointestinalHead & NeckSarcomaThoracic

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Gastrointestinal Stromal Tumors

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