Announcements Trials
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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Lymphoid 1Endocrine 1CNS 1

Conditions

Sarcoma 317Glioblastoma 176Gliosarcoma 166Astrocytoma 125Brain Neoplasms 117Osteosarcoma 101Glioma 97Central Nervous System Neoplasms 96Oligodendroglioma 92Neuroblastoma 88Neoplasms 87Melanoma 87Breast Neoplasms 81Ovarian Neoplasms 70Lymphoma 67Dendritic Cell Sarcoma, Interdigitating 64Sarcoma, Ewing 63Rhabdomyosarcoma 63Recurrence 63Carcinoma, Non-Small-Cell Lung 63Precursor Cell Lymphoblastic Leukemia-Lymphoma 59Burkitt Lymphoma 59Lymphoma, Non-Hodgkin 55Medulloblastoma 53Colorectal Neoplasms 53Wilms Tumor 52Pancreatic Neoplasms 51Neoplasm Metastasis 49Lymphoma, Large B-Cell, Diffuse 47Carcinoma, Hepatocellular 44

Interventions

Dexamethasone 1Calcium Dobesilate 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Prolactinoma × Sarcoma × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

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