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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 109Lymphoid 29Other hematologic neoplasm 16CNS 2Sarcoma 1Myeloid 1Endocrine 1

Conditions

Sarcoma 5Dendritic Cell Sarcoma, Interdigitating 5Neoplasms 4Lymphoma 4Burkitt Lymphoma 3Vomiting 2Nausea 2Lymphoma, Non-Hodgkin 2Liposarcoma 2Wilms Tumor 1Spinal Cord Neoplasms 1Rhabdoid Tumor 1Recurrence 1Prolactinoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pituitary Neoplasms 1Osteosarcoma 1Optic Nerve Glioma 1Oligodendroglioma 1Neoplasms, Connective and Soft Tissue 1Neoplasms by Histologic Type 1Neoplasm Metastasis 1Medulloblastoma 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Liposarcoma, Myxoid 1Leukemia, Large Granular Lymphocytic 1Leukemia 1

Interventions

Cyclophosphamide 39Peripheral Blood Stem Cell Transplantation 32fludarabine phosphate 30Busulfan 26Filgrastim 24Cyclosporine 24Mycophenolic Acid 22Antilymphocyte Serum 22Radiotherapy 20Melphalan 16Whole-Body Irradiation 15Tacrolimus 14Methylprednisolone 14Methotrexate 13Cord Blood Stem Cell Transplantation 12Etoposide 10sargramostim 5Thiotepa 5Temozolomide 5Sirolimus 5Rituximab 5Bevacizumab 5aldesleukin 4Therapeutics 4Granulocyte Colony-Stimulating Factor 4Cytarabine 4Carmustine 4pembrolizumab 3Vincristine 3Topotecan 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Recurrence × Dexamethasone × Sarcoma × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

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