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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Sarcoma 17Osteosarcoma 6Neuroectodermal Tumors, Primitive, Peripheral 4Wilms Tumor 3Rhabdoid Tumor 3Hepatoblastoma 3Vomiting 2Sarcoma, Ewing 2Rhabdomyosarcoma 2Retinoblastoma 2Neuroblastoma 2Neoplasms, Germ Cell and Embryonal 2Neoplasms 2Nausea 2Melanoma 2Medulloblastoma 2Lymphoma 2Dendritic Cell Sarcoma, Interdigitating 2Central Nervous System Neoplasms 2Carcinoma, Renal Cell 2Carcinoma, Hepatocellular 2Burkitt Lymphoma 2Stomach Neoplasms 1Sarcoma, Myeloid 1Sarcoma, Clear Cell 1Recurrence 1Rectal Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Neoplasms 1Optic Nerve Glioma 1

Interventions

Cyclophosphamide 4Topotecan 3Ifosfamide 3Doxorubicin 3seclidemstat 2pazopanib 2Biopsy 2tebentafusp 1selinexor 1pembrolizumab 1pegylated granulocyte colony-stimulating factor 1fludarabine phosphate 1fludarabine 1dostarlimab 1devimistat 1cobimetinib 1cabozantinib 1atezolizumab 1Zoledronic Acid 1X-Rays 1Vemurafenib 1Sunitinib 1Specimen Handling 1Sirolimus 1Simvastatin 1Radiotherapy, Image-Guided 1Radiotherapy 1Radiation Dose Hypofractionation 1Radiation 1Proton Therapy 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Sarcoma, Clear Cell × Mesna × Sarcoma × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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