Announcements Trials
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Phase

Phase 1 2Phase 1/2 1

Status

Unknown 2Completed 1

Sponsor Class

INDUSTRY 2OTHER 1

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3Other solid neoplasm 1Genitourinary 1Gastrointestinal 1CNS 1

Conditions

Sarcoma 15Sarcoma, Ewing 10Neuroblastoma 7Rhabdomyosarcoma 6Osteosarcoma 6Gliosarcoma 6Glioblastoma 6Brain Neoplasms 6Astrocytoma 6Neuroectodermal Tumors, Primitive, Peripheral 5Medulloblastoma 5Central Nervous System Neoplasms 5Glioma 4Wilms Tumor 3Sarcoma, Clear Cell 3Rhabdoid Tumor 3Recurrence 3Desmoplastic Small Round Cell Tumor 3Dendritic Cell Sarcoma, Interdigitating 3Burkitt Lymphoma 3Testicular Neoplasms 2Retinoblastoma 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Ovarian Neoplasms 2Optic Nerve Glioma 2Oligodendroglioma 2Myoepithelioma 2Meningeal Carcinomatosis 2Malignant mesenchymal tumor 2Lymphoma 2

Interventions

Cyclophosphamide 4Topotecan 3Ifosfamide 3Doxorubicin 3seclidemstat 2pazopanib 2Biopsy 2tebentafusp 1selinexor 1pembrolizumab 1pegylated granulocyte colony-stimulating factor 1fludarabine phosphate 1fludarabine 1dostarlimab 1devimistat 1cobimetinib 1cabozantinib 1atezolizumab 1Zoledronic Acid 1X-Rays 1Vemurafenib 1Sunitinib 1Specimen Handling 1Sirolimus 1Simvastatin 1Radiotherapy, Image-Guided 1Radiotherapy 1Radiation Dose Hypofractionation 1Radiation 1Proton Therapy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Sarcoma, Clear Cell × Topotecan × Sarcoma × Clear all
NCT03600649 2023-11-21

Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related Sarcomas

Salarius Pharmaceuticals, LLC

Phase 1 Unknown
50 enrolled
Sarcoma

Histiocytoma, Angiomatoid Fibrous, Chondrosarcoma, Extraskeletal Myxoid, Fibroma, Myoepithelioma, Sarcoma, Sarcoma, Ewing, Liposarcoma, Myxoid, Sarcoma, Clear Cell, Desmoplastic Small Round Cell Tumor

NCT05266196 2023-08-01

A Rollover Protocol to Allow for Continued Access to the LSD1 Inhibitor Seclidemstat (SP-2577)

Salarius Pharmaceuticals, LLC

Phase 1/2 Unknown
10 enrolled
Sarcoma

Histiocytoma, Angiomatoid Fibrous, Chondrosarcoma, Extraskeletal Myxoid, Myoepithelioma, Sarcoma, Ewing, Liposarcoma, Myxoid, Sarcoma, Clear Cell, Desmoplastic Small Round Cell Tumor

NCT02390843 2020-04-03

AflacST1402

Emory University

Phase 1 Completed
13 enrolled
CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Renal Cell, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Rhabdoid Tumor

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