Clinical Trials

Phase 1 Active not recruiting

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT02659930 2026-06-04

Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma

62 enrolled

Multi-centric Castleman's Disease, Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT04742387 2026-06-02

Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis

Active not recruiting

40 enrolled

Multi-centric Castleman's Disease, Acquired Immunodeficiency Syndrome, Bone Diseases, Metabolic, Sarcoma, Kaposi, Lymphoma, Primary Effusion

NCT05907759 2026-06-02

Daratumumab for Relapsed/Refractory Primary Effusion Lymphoma, Plasmablastic Lymphoma, and Multicentric Castleman Disease

Phase 2 Recruiting

28 enrolled

Multi-centric Castleman's Disease, Lymphoma, Non-Hodgkin, Sarcoma, Kaposi, Lymphoma, Primary Effusion

NCT04303117 2026-06-01

PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Phase 1/2 Recruiting

80 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT06375122 2026-06-01

Natural History Study of Kaposi Sarcoma

Recruiting

150 enrolled

Sarcoma, Kaposi

NCT03300830 2026-05-29

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease

Recruiting

280 enrolled

Phase 1 Active not recruiting

Acquired Immunodeficiency Syndrome, Castleman Disease, Immunologic Deficiency Syndromes, Sarcoma, Kaposi

NCT04514484 2026-05-28

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

8 enrolled 32 charts

BreastDermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Prostatic Neoplasms, Sarcoma, Kaposi, HIV Infections, Carcinoma, Medullary, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT07308886 2026-05-08

Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)

Phase 2 Recruiting

55 enrolled

Lymphoproliferative Disorders, Sarcoma, Kaposi

NCT04941274 2026-05-05

Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma

Phase 1/2 Recruiting

111 enrolled

GastrointestinalSarcomaThoracic

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT02408861 2026-01-21

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Phase 1 Terminated

79 enrolled 24 charts

Anus Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Sarcoma, Kaposi, HIV Infections

NCT02595866 2024-08-09

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

DermatologicGastrointestinalLymphoidSarcomaThoracic

58 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Neoplasm Metastasis, Neoplasms, Recurrence, Sarcoma, Kaposi, HIV Infections

NCT00339937 2024-03-22

Studies of Human Herpesvirus 8 and Kaposi's Sarcoma in Sicily

4,622 enrolled

Sarcoma, Kaposi

NCT00019188 2024-03-04

Interleukin-12 in Treating Patients With AIDS-Related Kaposi's Sarcoma

DermatologicSarcoma

AIDS-related Kaposi sarcoma, Neoplasms, Sarcoma, Kaposi, Skin Neoplasms

NCT01495598 2022-11-01

Pomalidomide for Kaposi Sarcoma in People With or Without HIV

28 enrolled 23 charts

Sarcoma, Kaposi

NCT01057121 2022-02-08

Lenalidomide in Treating Patients With AIDS-Associated Kaposi's Sarcoma

38 enrolled 11 charts

AIDS-related Kaposi sarcoma, Sarcoma, Kaposi, HIV Infections

NCT00000987 2021-11-04

A Study of Chemotherapy Plus Azidothymidine in the Treatment of Kaposi's Sarcoma in Patients With AIDS

36 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000994 2021-11-04

A Study of AZT in HIV-Infected Patients With AIDS-Related Kaposi's Sarcoma

Phase 3 Completed

240 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections, AIDS-Related Opportunistic Infections

NCT00000996 2021-11-04

A Study of Doxorubicin in the Treatment of AIDS-Related Kaposi's Sarcoma

48 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00001113 2021-11-04

A Study of AZT Plus Human Interferon Alpha in the Treatment of AIDS-Related Kaposi's Sarcoma

48 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000660 2021-11-03

Phase I Study of Weekly Oral VP-16 for AIDS-Associated Kaposi's Sarcoma

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000681 2021-11-03

A Phase I Study of the Combination of Recombinant GM-CSF, AZT, and Chemotherapy (ABV) (Adriamycin, Bleomycin, Vincristine) in AIDS and Kaposi's Sarcoma

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000687 2021-11-03

Phase II Study of Zidovudine and Recombinant Alpha-2A Interferon in the Treatment of Patients With AIDS-Associated Kaposi's Sarcoma

60 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000725 2021-11-03

A Phase I Study of AZT and Human Interferon Alpha (Recombinant Alpha-2A and Lymphoblastoid) in the Treatment of AIDS-Associated Kaposi's Sarcoma

56 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000763 2021-11-03

A Phase I Study of TNP-470 in the Treatment of AIDS-Associated Kaposi's Sarcoma

42 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000694 2021-11-02

A Phase I Trial of Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (rHuGM-CSF), Recombinant Alpha Interferon and Azidothymidine (AZT) in AIDS-Associated Kaposi's Sarcoma

18 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000695 2021-11-02

Open Label Phase I Study To Evaluate the Safety of Combination Therapy With AZT and Interferon-Beta in Patients With AIDS Related Kaposi's Sarcoma

36 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00001114 2021-11-01

The Safety and Effectiveness of Interferon Alfa-2B Plus Didanosine in Patients With Kaposi's Sarcoma

90 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000954 2021-10-29

A Study of Chemotherapy Plus ddI or ddC in the Treatment of AIDS-Related Kaposi's Sarcoma

72 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000769 2021-10-28

A Phase I/II Study of Recombinant Interleukin-4 in AIDS and Kaposi's Sarcoma

48 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00000807 2021-10-28

Phase II Evaluation of Low-Dose Oral Etoposide for the Treatment of Relapsed or Progressed AIDS-Related Kaposi's Sarcoma After Systemic Chemotherapy

41 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi, HIV Infections

NCT00339326 2021-03-12

Risk Factors for Non-HIV-Related Kaposi s Sarcoma

1,383 enrolled

Sarcoma, Kaposi

NCT00395278 2020-12-11

Development of Serologic Assays for Human Herpes Virus-8

394 enrolled

Sarcoma, Kaposi, HIV Infections

NCT01441063 2020-10-27

Tocilizumab for KSHV-Associated Multicentric Castleman Disease

8 enrolled 18 charts

Multi-centric Castleman's Disease, Acquired Immunodeficiency Syndrome, Castleman Disease, Sarcoma, Kaposi

NCT00026793 2020-07-08

Assessment of Blood Vessel Density in Kaposi's Sarcoma Lesions

29 enrolled 11 charts

Sarcoma, Kaposi

NCT00006171 2019-12-12

Effects of Potent Antiretroviral Therapy on Kaposi s Sarcoma

Acquired Immunodeficiency Syndrome, HIV Seropositivity, Neoplasms, Sarcoma, Kaposi, HIV Infections

NCT00287495 2019-12-12

BAY 43-9006 (Sorafenib) to Treat Patients With Kaposi's Sarcoma

Phase 1 Terminated

10 enrolled

Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT01154452 2018-08-15

Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma

78 enrolled 11 charts

GastrointestinalSarcoma

Malignant mesenchymal tumor, Chondrosarcoma, Extraskeletal Myxoid, Chondrosarcoma, Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Sarcoma, Alveolar Soft Part, Neuroectodermal Tumors, Primitive, Peripheral, Neurofibrosarcoma, Hemangioendothelioma, Epithelioid, Gastrointestinal Stromal Tumors, Histiocytoma, Malignant Fibrous, Desmoplastic Small Round Cell Tumor

NCT00923936 2018-07-24

Pilot Study of Liposomal Doxorubicin Combined With Bevacizumab Followed by Bevacizumab Monotherapy in Adults With Advanced Kaposi s Sarcoma

16 enrolled 13 charts

Sarcoma, Kaposi

NCT01016730 2018-02-20

Bortezomib in Treating Patients With Relapsed or Refractory AIDS-Related Kaposi Sarcoma

AIDS-related Kaposi sarcoma, Sarcoma, Kaposi, HIV Infections

NCT00055237 2017-09-06

Bevacizumab to Treat Kaposi's Sarcoma in HIV-Positive and HIV-Negative Patients

19 enrolled 10 charts

Neoplasms, Sarcoma, Kaposi, HIV Infections

NCT00001560 2017-07-02

Clinical, Laboratory and Epidemiologic Pilot Studies of Individuals at High Risk for Viral-Associated Cancers