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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Gynecologic 1Genitourinary 1Gastrointestinal 1CNS 1

Conditions

Gliosarcoma 15Glioblastoma 15Central Nervous System Neoplasms 10Brain Neoplasms 9Astrocytoma 8Glioma 6Oligodendroglioma 4Sarcoma 2Ependymoma 2Wilms Tumor 1Testicular Neoplasms 1Teratoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Ovarian Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Optic Nerve Glioma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Medulloblastoma 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Lymphoma 1Liver Neoplasms 1Leukemia, Lymphocytic, Chronic, B-Cell 1

Interventions

Filgrastim 8Carboplatin 8Peripheral Blood Stem Cell Transplantation 6Etoposide 5Thiotepa 4Melphalan 4Cyclophosphamide 4Busulfan 4Temozolomide 3Radiotherapy 3Polymerase Chain Reaction 3Ifosfamide 3Granulocyte Colony-Stimulating Factor 3etoposide phosphate 2aflibercept 2Topotecan 2Therapeutics 2Psychiatric Rehabilitation 2Magnetic Resonance Spectroscopy 2Itraconazole 2Flow Cytometry 2Carmustine 2Bone Marrow Transplantation 2Blood Specimen Collection 2Amplified Fragment Length Polymorphism Analysis 2Amifostine 2trioctyl phosphine oxide 1tremelimumab 1trastuzumab deruxtecan 1thymoglobulin 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Testicular Neoplasms × O(6)-benzylguanine × Sarcoma × Clear all
NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

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