Announcements Trials
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Phase

Phase 2 4Phase NA 3Phase 1 3Phase 3 2

Status

Withdrawn 1Terminated 1Completed 1

Sponsor Class

NIH 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Plasma cell 139Lymphoid 60Other hematologic neoplasm 41Genitourinary 8Gastrointestinal 6Myeloid 5CNS 5Tumor-Agnostic 4Other solid neoplasm 4Dermatologic 4Sarcoma 3Breast 3Thoracic 2Head & Neck 2Gynecologic 1Endocrine 1Classical hematology 1

Conditions

Sarcoma 2Neoplasms 2Wilms Tumor 1Spinal Cord Neoplasms 1Rhabdoid Tumor 1Recurrence 1Prolactinoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pituitary Neoplasms 1Osteosarcoma 1Optic Nerve Glioma 1Oligodendroglioma 1Neoplasms, Connective and Soft Tissue 1Neoplasms by Histologic Type 1Medulloblastoma 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma 1Leukemia, Large Granular Lymphocytic 1Familial ependymoma 1Dendritic Cell Sarcoma, Interdigitating 1Choroid Plexus Neoplasms 1Burkitt Lymphoma 1Brain Neoplasms 1Astrocytoma 1Adenoma, Chromophobe 1Adenoma, Basophil 1Adenoma, Acidophil 1

Interventions

Temozolomide 62Cyclophosphamide 59Radiotherapy 47Doxorubicin 36Filgrastim 26Irinotecan 24Radiation 23Gemcitabine 23fludarabine 22Magnetic Resonance Spectroscopy 20Imatinib Mesylate 19Etoposide 18pembrolizumab 16Cisplatin 15Carboplatin 15Biopsy 15Bevacizumab 15Specimen Handling 14fludarabine phosphate 12Nivolumab 12Leucovorin 12Ipilimumab 12Granulocyte Colony-Stimulating Factor 12Chemotherapy, Adjuvant 12pazopanib 11Vincristine 11Ifosfamide 11Melphalan 10Erlotinib Hydrochloride 10Docetaxel 10

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Dexamethasone × Sarcoma × Clear all
NCT01236586 2017-07-02

RO4929097 in Children With Relapsed/Refractory Solid or CNS Tumors, Lymphoma, or T-Cell Leukemia

National Institutes of Health Clinical Center (CC)

Phase 1 Withdrawn
CNSGenitourinaryLymphoidSarcoma

Brain Neoplasms, Lymphoma, Neoplasms, Wilms Tumor, Sarcoma, Osteosarcoma

NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT00102609 2013-01-10

A Safety Study Utilizing Yondelis and Doxorubicin in Patients With a Type of Cancer Called Soft Tissue Sarcoma

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Phase 1 Completed
41 enrolled
Sarcoma

Neoplasms, Neoplasms by Histologic Type, Sarcoma, Neoplasms, Connective and Soft Tissue

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