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Phase

Phase 2 4Phase EARLY_PHASE1 1

Status

Withdrawn 1Terminated 1Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 4INDUSTRY 1

Study Type

Interventional 5

Sponsor

Cancer Type

Breast 437Gynecologic 50Genitourinary 6Thoracic 5Sarcoma 5Tumor-Agnostic 4Other solid neoplasm 4Other 4Gastrointestinal 4Lymphoid 2Head & Neck 2Endocrine 2CNS 1

Conditions

Breast Neoplasms 3Prostatic Neoplasms 2Leiomyosarcoma 2Uterine Neoplasms 1Triple Negative Breast Neoplasms 1Sarcoma 1Pathologic Complete Response 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Neoplasms 1Liposarcoma 1Hemangiosarcoma 1Colorectal Neoplasms 1Adenocarcinoma of Lung 1

Interventions

Radiotherapy 220Doxorubicin 210Cyclophosphamide 210Temozolomide 182Ifosfamide 121Filgrastim 111Imatinib Mesylate 104Etoposide 101Vincristine 92Gemcitabine 89Bevacizumab 83Magnetic Resonance Spectroscopy 80Irinotecan 79pembrolizumab 75Radiation 69Carboplatin 65Methotrexate 62pazopanib 61Nivolumab 58Cisplatin 58fludarabine phosphate 57Peripheral Blood Stem Cell Transplantation 57Surgical Procedures, Operative 56Specimen Handling 56Trabectedin 52Docetaxel 50Biopsy 50Busulfan 49Melphalan 46Paclitaxel 44

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Letrozole × Sarcoma × Clear all
NCT01042379 2026-05-06

I-SPY

QuantumLeap Healthcare Collaborative

Phase 2 Recruiting
5,000 enrolled
BreastSarcoma

Pathologic Complete Response, Breast Neoplasms, Hemangiosarcoma, Neoplasms, Triple Negative Breast Neoplasms

NCT04557449 2025-10-01

CDK4i

Pfizer

Phase 2 Active not recruiting
362 enrolled
BreastGastrointestinalGenitourinarySarcomaThoracic

Adenocarcinoma of Lung, Breast Neoplasms, Liposarcoma, Prostatic Neoplasms, Colorectal Neoplasms

NCT05238831 2024-01-23

SMMART Adaptive Clinical Treatment (ACT) Trial

OHSU Knight Cancer Institute

Phase EARLY_PHASE1 Withdrawn
BreastGastrointestinalGenitourinaryGynecologicSarcoma

Breast Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma

NCT00414076 2018-11-20

Letrozole Versus Observation in Patients With Newly Diagnosed Uterine Leiomyosarcoma

M.D. Anderson Cancer Center

Phase 2 Terminated
9 enrolled 7 charts
GynecologicSarcoma

Leiomyosarcoma, Uterine Neoplasms

NCT00856050 2017-04-18

Letrozole in Women With Advanced Estrogen/Progesterone Receptor Positive Uterine Leiomyosarcoma

Dana-Farber Cancer Institute

Phase 2 Completed
27 enrolled 4 charts
Sarcoma

Leiomyosarcoma

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