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Phase

Phase 2 4Phase EARLY_PHASE1 1

Status

Terminated 1Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 3INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Breast 185Gynecologic 28Sarcoma 4Thoracic 3Genitourinary 3Gastrointestinal 3Tumor-Agnostic 1Other solid neoplasm 1Head & Neck 1Endocrine 1

Conditions

Leiomyosarcoma 2Breast Neoplasms 2Uterine Neoplasms 1Triple Negative Breast Neoplasms 1Prostatic Neoplasms 1Pathologic Complete Response 1Neoplasms 1Liposarcoma 1Hemangiosarcoma 1Colorectal Neoplasms 1Adenocarcinoma of Lung 1

Interventions

Cyclophosphamide 93Doxorubicin 92Radiotherapy 87Temozolomide 69Filgrastim 58Ifosfamide 55Bevacizumab 55Etoposide 48Gemcitabine 44Imatinib Mesylate 43Vincristine 40pembrolizumab 35pazopanib 34Peripheral Blood Stem Cell Transplantation 31Methotrexate 31Nivolumab 30Carboplatin 30fludarabine phosphate 29Irinotecan 29Cisplatin 28Paclitaxel 26Melphalan 26Magnetic Resonance Spectroscopy 26Docetaxel 25Busulfan 25Trabectedin 24apatinib 22Specimen Handling 21Sirolimus 21Antilymphocyte Serum 21

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 2 × Letrozole × Sarcoma × Clear all
NCT01042379 2026-05-06

I-SPY

QuantumLeap Healthcare Collaborative

Phase 2 Recruiting
5,000 enrolled
BreastSarcoma

Pathologic Complete Response, Breast Neoplasms, Hemangiosarcoma, Neoplasms, Triple Negative Breast Neoplasms

NCT04557449 2025-10-01

CDK4i

Pfizer

Phase 2 Active not recruiting
362 enrolled
BreastGastrointestinalGenitourinarySarcomaThoracic

Adenocarcinoma of Lung, Breast Neoplasms, Liposarcoma, Prostatic Neoplasms, Colorectal Neoplasms

NCT00414076 2018-11-20

Letrozole Versus Observation in Patients With Newly Diagnosed Uterine Leiomyosarcoma

M.D. Anderson Cancer Center

Phase 2 Terminated
9 enrolled 7 charts
GynecologicSarcoma

Leiomyosarcoma, Uterine Neoplasms

NCT00856050 2017-04-18

Letrozole in Women With Advanced Estrogen/Progesterone Receptor Positive Uterine Leiomyosarcoma

Dana-Farber Cancer Institute

Phase 2 Completed
27 enrolled 4 charts
Sarcoma

Leiomyosarcoma

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