Announcements Trials
Browse Landscape

Phase

Phase 1/2 5Phase 3 1Phase 2 1

Status

Recruiting 2Withdrawn 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 3INDUSTRY 2

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 7Sarcoma 5Gynecologic 3Other solid neoplasm 1NET 1Gastrointestinal 1Endocrine 1CNS 1Breast 1

Conditions

Sarcoma, Ewing 3Sarcoma 3Neoplasms 2Stomach Neoplasms 1Neuroendocrine Tumors 1Mesothelioma 1Glioblastoma 1Gastro-enteropancreatic neuroendocrine tumor 1Endometrial Neoplasms 1Desmoplastic Small Round Cell Tumor 1Colorectal Neoplasms 1Carcinoma, Ovarian Epithelial 1

Interventions

Temozolomide 33Radiotherapy 32pembrolizumab 18Cyclophosphamide 18Irinotecan 16Gemcitabine 16Doxorubicin 16Nivolumab 11Docetaxel 11Sirolimus 10Imatinib Mesylate 10Ifosfamide 10Filgrastim 10Radiation 9Bevacizumab 9Vincristine 8Carboplatin 8pazopanib 7Everolimus 7temsirolimus 6atezolizumab 6Peripheral Blood Stem Cell Transplantation 6Etoposide 6fludarabine phosphate 5Vorinostat 5Specimen Handling 5Radiotherapy, Conformal 5PM 01183 5Ipilimumab 5Erlotinib Hydrochloride 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1/2 × PM 01183 × Sarcoma × Clear all
NCT05099666 2026-04-13

Lurbinectedin + Doxorubicin In Leiomyosarcoma

Massachusetts General Hospital

Phase 1/2 Active not recruiting
62 enrolled
Sarcoma

Sarcoma

NCT05918640 2026-03-31

LiFFT

Children's Hospital of Philadelphia

Phase 1/2 Recruiting
63 enrolled
Sarcoma

Neoplasms, Sarcoma, Ewing, Desmoplastic Small Round Cell Tumor

NCT05734066 2026-02-03

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

Jazz Pharmaceuticals

Phase 1/2 Recruiting
60 enrolled
Sarcoma

Sarcoma, Sarcoma, Ewing

NCT02611024 2025-07-09

Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors

PharmaMar

Phase 1/2 Completed
316 enrolled
CNSEndocrineGastrointestinalGynecologicNETOther solid neoplasmSarcomaThoracic

Gastro-enteropancreatic neuroendocrine tumor, Carcinoma, Ovarian Epithelial, Glioblastoma, Mesothelioma, Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Neuroendocrine Tumors

NCT05042934 2022-02-10

Lurbinectedin With or Without Irinotecan in Treating Patients With Relapsed or High Risk Metastatic Ewing Sarcoma

M.D. Anderson Cancer Center

Phase 1/2 Withdrawn
Sarcoma

Sarcoma, Ewing

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