Announcements Trials
Browse Landscape

Phase

Phase 1 3Phase 2 2Phase 3 1

Status

Completed 5Withdrawn 1

Sponsor Class

INDUSTRY 5OTHER 1

Study Type

Interventional 6

Sponsor

Cancer Type

Sarcoma 6Gynecologic 6Lymphoid 5Breast 5Other solid neoplasm 3CNS 3Tumor-Agnostic 2Thoracic 2Plasma cell 2Genitourinary 2Other hematologic neoplasm 1Myeloid 1Gastrointestinal 1

Conditions

Sarcoma 5Osteosarcoma 1Neoplasms 1Neoplasm Metastasis 1Liposarcoma 1Leiomyosarcoma 1Gliosarcoma 1Glioma 1Glioblastoma 1Bone Neoplasms 1

Interventions

Radiotherapy 221Cyclophosphamide 211Doxorubicin 210Temozolomide 182Ifosfamide 121Filgrastim 111Imatinib Mesylate 104Etoposide 101Vincristine 92Gemcitabine 89Bevacizumab 83Magnetic Resonance Spectroscopy 81Irinotecan 79pembrolizumab 75Radiation 70Carboplatin 65Methotrexate 62pazopanib 61Nivolumab 58Cisplatin 58fludarabine phosphate 57Surgical Procedures, Operative 57Peripheral Blood Stem Cell Transplantation 57Specimen Handling 56Trabectedin 52Docetaxel 50Biopsy 50Busulfan 49Melphalan 46Paclitaxel 44

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
ridaforolimus × Sarcoma × Clear all
NCT00087451 2015-08-19

Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED)

Merck Sharp & Dohme LLC

Phase 1 Completed
11 enrolled
CNSSarcoma

Glioblastoma, Glioma, Gliosarcoma

NCT00288431 2015-07-22

Safety, Tolerability and Maximum Tolerated Dose of Oral AP23573 in Combination With Doxorubicin (8669-015)

Merck Sharp & Dohme LLC

Phase 1 Completed
37 enrolled
Sarcoma

Neoplasms, Sarcoma

NCT01010672 2015-04-30

Phase II Study of Ridaforolimus (MK-8669) With Metastatic Bone or Soft-tissue Sarcoma Patients (MK-8669-030 AM1)

Merck Sharp & Dohme LLC

Phase 2 Completed
50 enrolled
Sarcoma

Sarcoma

NCT00093080 2015-02-13

Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED)

Merck Sharp & Dohme LLC

Phase 2 Completed
216 enrolled
Sarcoma

Leiomyosarcoma, Liposarcoma, Neoplasm Metastasis, Sarcoma, Osteosarcoma

NCT00538239 2015-02-13

SUCCEED

Merck Sharp & Dohme LLC

Phase 3 Completed
711 enrolled
Sarcoma

Bone Neoplasms, Sarcoma

NCT01296659 2012-07-12

Study of Oral Ridaforolimus in Combination With Standard Chemotherapy for Soft Tissue Sarcoma

The University of Texas Health Science Center at San Antonio

Phase 1 Withdrawn
Sarcoma

Sarcoma

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