Announcements Trials
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Phase

Phase 2 2Phase 1 2Phase 1/2 1

Status

Completed 5

Sponsor Class

OTHER 3NIH 2

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 28Head & Neck 14Gastrointestinal 13CNS 13Genitourinary 10Breast 9Endocrine 7Tumor-Agnostic 6Sarcoma 5Other solid neoplasm 3Gynecologic 3Plasma cell 1Other neoplasm 1Other hematologic neoplasm 1NET 1Lymphoid 1Dermatologic 1

Conditions

Gliosarcoma 4Glioblastoma 4Glioma 3Brain Neoplasms 3Oligodendroglioma 1GIST 1Disease Progression 1Astrocytoma 1

Interventions

Radiotherapy 221Cyclophosphamide 211Doxorubicin 210Temozolomide 182Ifosfamide 121Filgrastim 111Imatinib Mesylate 104Etoposide 101Vincristine 92Gemcitabine 89Bevacizumab 83Magnetic Resonance Spectroscopy 81Irinotecan 79pembrolizumab 75Radiation 70Carboplatin 65Methotrexate 62pazopanib 61Nivolumab 58Cisplatin 58fludarabine phosphate 57Surgical Procedures, Operative 57Peripheral Blood Stem Cell Transplantation 57Specimen Handling 56Trabectedin 52Docetaxel 50Biopsy 50Busulfan 49Melphalan 46Paclitaxel 44

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
vandetanib × Sarcoma × Clear all
NCT02015065 2020-03-30

Phase II Trial of Vandetanib in Children and Adults With Wild-Type Gastrointestinal Stromal Tumors

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
9 enrolled 14 charts
Sarcoma

GIST

NCT00441142 2019-03-05

Zactima

Dana-Farber Cancer Institute

Phase 1/2 Completed
119 enrolled 15 charts
CNSSarcoma

Glioblastoma, Gliosarcoma

NCT00995007 2016-03-29

A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
112 enrolled 12 charts
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma, Disease Progression

NCT00613223 2013-02-20

Ph I Dose Escalation Trial of Vandetanib in Combo w Etoposide for Malignant Gliomas

Duke University

Phase 1 Completed
49 enrolled
CNSSarcoma

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00613054 2012-12-05

Ph I Zactima + Imatinib Mesylate & Hydroxyurea for Pts w Recurrent Malignant Glioma

Duke University

Phase 1 Completed
27 enrolled
CNSSarcoma

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

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