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Phase

Phase 1/2 2Phase 2/3 1Phase 2 1Phase 1 1

Status

Completed 3Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 2NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Breast 27Gynecologic 25Gastrointestinal 18Thoracic 15CNS 9Lymphoid 8Genitourinary 6Sarcoma 5Other solid neoplasm 5Other hematologic neoplasm 5Dermatologic 5Tumor-Agnostic 3Myeloid 2Head & Neck 2Endocrine 2Plasma cell 1NET 1

Conditions

Gliosarcoma 4Glioblastoma 4Central Nervous System Neoplasms 2Astrocytoma 2Triple Negative Breast Neoplasms 1Pathologic Complete Response 1Oligodendroglioma 1Neoplasms 1Hemangiosarcoma 1Glioma 1Ependymoma 1Breast Neoplasms 1Brain Neoplasms 1

Interventions

Radiotherapy 215Cyclophosphamide 210Doxorubicin 207Temozolomide 181Ifosfamide 121Filgrastim 111Etoposide 101Imatinib Mesylate 99Vincristine 92Gemcitabine 89Bevacizumab 83Irinotecan 79Magnetic Resonance Spectroscopy 78pembrolizumab 75Radiation 66Carboplatin 65pazopanib 60Methotrexate 60Nivolumab 58Cisplatin 58fludarabine phosphate 56Peripheral Blood Stem Cell Transplantation 56Specimen Handling 53Docetaxel 50Busulfan 48Trabectedin 47Biopsy 47Melphalan 46Surgical Procedures, Operative 44Paclitaxel 44

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × veliparib × Sarcoma × Clear all
NCT01042379 2026-05-06

I-SPY

QuantumLeap Healthcare Collaborative

Phase 2 Recruiting
5,000 enrolled
BreastSarcoma

Pathologic Complete Response, Breast Neoplasms, Hemangiosarcoma, Neoplasms, Triple Negative Breast Neoplasms

NCT02152982 2026-04-28

Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

National Cancer Institute (NCI)

Phase 2/3 Active not recruiting
447 enrolled 20 charts
CNSSarcoma

Glioblastoma, Gliosarcoma

NCT01514201 2019-08-13

Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas

National Cancer Institute (NCI)

Phase 1/2 Completed
66 enrolled 24 charts
CNSSarcoma

Astrocytoma, Glioblastoma, Gliosarcoma

NCT00770471 2018-06-27

ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 1 Completed
24 enrolled
CNSSarcoma

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01026493 2017-07-02

Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma

Radiation Therapy Oncology Group

Phase 1/2 Completed
257 enrolled 16 charts
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

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