Clinical Trials

25 enrolled 15 charts

NCT03740529 2026-01-27

A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL

LymphoidOther hematologic neoplasmSarcoma

803 enrolled 4 FDA

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT02805725 2026-01-14

TARMIC

50 enrolled 15 charts

NCT03993678 2025-12-30

Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Advanced Solid Tumors.

28 enrolled

DermatologicSarcoma

Melanoma, Sarcoma

NCT06562673 2025-12-29

IACE-OS

10 enrolled

Bone Neoplasms, Osteosarcoma

NCT04067115 2025-12-17

U01CA236220

37 enrolled

Sarcoma, Ewing

NCT03526679 2025-12-05

LEADER

30 enrolled 9 charts

Leiomyosarcoma, Liposarcoma, Sarcoma

NCT02875548 2025-11-04

TRuST

LymphoidOther solid neoplasmSarcomaThoracic

58 enrolled

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mesothelioma, Sarcoma, Synovial, Lymphoma, Large B-Cell, Diffuse

NCT03174197 2025-09-24

Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

60 enrolled

Glioblastoma, Gliosarcoma

NCT03425279 2025-09-23

CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma

245 enrolled

Neoplasms, Dermatofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT01027910 2025-07-24

PCI-24781 in Combination With Doxorubicin to Treat Sarcoma

20 enrolled 10 charts

NCT02611024 2025-07-09

Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors

CNSEndocrineGastrointestinalGynecologicNETOther solid neoplasmSarcomaThoracic

316 enrolled

Gastro-enteropancreatic neuroendocrine tumor, Carcinoma, Ovarian Epithelial, Glioblastoma, Mesothelioma, Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Neuroendocrine Tumors

NCT00742963 2025-05-13

Dose-Escalation Study of TH-302 in Combination With Doxorubicin to Treat Patients With Advanced Soft Tissue Sarcoma

107 enrolled 7 charts

NCT02632448 2025-05-02

A Study of LY2880070 in Participants With Advanced or Metastatic Cancer

BreastGastrointestinalGynecologicSarcoma

229 enrolled

Breast Neoplasms, Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Triple Negative Breast Neoplasms

NCT03058289 2025-02-27

IT-01

BreastGastrointestinalHead & NeckLymphoidSarcomaThoracic

111 enrolled 21 charts

Diabetes Mellitus, Insulin-Dependent, 12, Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Colonic Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Pancreatic Neoplasms, Sarcoma

NCT04095221 2025-02-20

A Study of the Drugs Prexasertib, Irinotecan, and Temozolomide in People With Desmoplastic Small Round Cell Tumor and Rhabdomyosarcoma

21 enrolled

Rhabdomyosarcoma, Desmoplastic Small Round Cell Tumor

NCT03190174 2025-02-17

Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

DermatologicGastrointestinalGenitourinarySarcomaThoracic

34 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Chordoma, Carcinoma, Hepatocellular, Melanoma, Sarcoma, Sarcoma, Ewing, Colorectal Neoplasms, Desmoid Tumors, Perivascular Epithelioid Cell Neoplasms

NCT02401815 2025-02-14

CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors

51 enrolled 32 charts

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT03150862 2025-02-04

A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma

116 enrolled 31 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Nervous System Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Gliosarcoma

NCT03997968 2024-12-24

A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors

BreastGastrointestinalGynecologicHead & NeckLymphoidPlasma cellSarcomaThoracic

169 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Head and Neck Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Lymphoma, Mantle-Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT01291420 2024-12-09

Dendritic Cell Vaccination for Patients with Solid Tumors

BreastCNSGastrointestinalGenitourinaryOther solid neoplasmSarcomaThoracic

48 enrolled

Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Renal Cell, Glioblastoma, Sarcoma, Colorectal Neoplasms

NCT03250325 2024-11-20

Study of TBI-1301 (NY-ESO-1 T Cell Receptor Gene Transduced Autologous T Lymphocytes) in Patients with Synovial Sarcoma

8 enrolled

Sarcoma, Synovial

NCT04887298 2024-10-24

Study of Liposomal Annamycin for the Treatment of Subjects with Soft-Tissue Sarcomas (STS) with Pulmonary Metastases

36 enrolled

NCT03345485 2024-10-21

EDO-S101

BreastGastrointestinalGynecologicSarcomaThoracic

71 enrolled 39 charts

Breast Neoplasms, Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Recurrence, Sarcoma, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT03277924 2024-08-13

ImmunoSarc

197 enrolled

Chondrosarcoma, Extraskeletal Myxoid, Bone Neoplasms, Chondrosarcoma, Hemangioendothelioma, Hemangiosarcoma, Leiomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Hemangioendothelioma, Epithelioid, Histiocytoma, Malignant Fibrous, Solitary Fibrous Tumors

NCT03338959 2024-07-23

Pembrolizumab and Radiation Therapy in Treating Patients With Intermediate or High-Grade Soft Tissue Sarcoma

27 enrolled 10 charts

NCT03320330 2024-07-15

Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors

26 enrolled 20 charts

Osteosarcoma

NCT02549937 2024-07-10

A Multi-Center, Open-Label Study of Surufatinib (HMPL-012) in Patients With Advanced Solid Tumors

130 enrolled 30 charts

EndocrineSarcoma

Carcinoid Tumor, Neoplasms, Sarcoma, Neuroectodermal Tumors, Primitive

NCT01837862 2024-07-05

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

36 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Gliosarcoma, Optic Nerve Glioma

NCT03508726 2024-06-27

High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas

25 enrolled 11 charts

NCT02453191 2024-06-20

TVEC and Preop Radiation for Sarcoma (4 ml Dose)

30 enrolled 12 charts

NCT05093322 2024-06-07

A Study of Surufatinib in Combination With Gemcitabine in Pediatric, Adolescent, and Young Adult Patients With Recurrent or Refractory Solid Tumors

13 enrolled 17 charts

LymphoidSarcoma

Lymphoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma

NCT02235701 2024-05-29

Study to Investigate the Safety and Activity of Aldoxorubicin Plus Ifosfamide/Mesna in Subjects With Metastatic Soft Tissue Sarcoma

70 enrolled 10 charts

Neoplasm Metastasis, Sarcoma

NCT03802084 2024-05-13

A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor

24 enrolled

Desmoid Tumors

NCT04742959 2024-04-26

Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

203 enrolled

Urinary Bladder Neoplasms, Gallbladder Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02052648 2024-03-27

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

160 enrolled 21 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT01386619 2024-03-19

NK DLI in Patients After Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation (HSCT)

CNSLymphoidMyeloidOther hematologic neoplasmSarcoma

15 enrolled

Lymphoma, Myelodysplastic Syndromes, Neuroblastoma, Rhabdomyosarcoma, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00019188 2024-03-04

Interleukin-12 in Treating Patients With AIDS-Related Kaposi's Sarcoma

DermatologicSarcoma

AIDS-related Kaposi sarcoma, Neoplasms, Sarcoma, Kaposi, Skin Neoplasms

NCT04310410 2024-02-07

PRE-FURTHER

10 enrolled

Bone Neoplasms, Neoplasm Metastasis, Neoplasms, Pain, Radiation Injuries

NCT02304458 2023-10-17

Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

CNSDermatologicLymphoidSarcoma

140 enrolled 23 charts

Hodgkin Disease, Lymphoma, Non-Hodgkin, Melanoma, Neuroblastoma, Rhabdomyosarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT02095132 2023-09-26

Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors

76 enrolled 25 charts

Medulloblastoma, Neuroblastoma, Pinealoma, Rhabdomyosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive

NCT03245151 2023-08-30

Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors

64 enrolled 29 charts

Glioma, Recurrence, Rhabdomyosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT02988817 2023-08-01

Enapotamab Vedotin (HuMax-AXL-ADC) Safety Study in Patients With Solid Tumors

DermatologicGynecologicHead & NeckSarcomaThoracic

306 enrolled 51 charts

Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Melanoma, Ovarian Neoplasms, Sarcoma, Thyroid Neoplasms, Endometrial Neoplasms

NCT02432274 2023-07-11

Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma

117 enrolled 32 charts

Neoplasms, Osteosarcoma

NCT01265030 2023-06-26

A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis

9 enrolled 5 charts

Desmoid Tumors

NCT02797977 2023-06-22

A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects

Classical hematologySarcomaThoracic

153 enrolled

Fanconi Anemia, Sarcoma, Small Cell Lung Carcinoma

NCT02661282 2023-06-18

Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma

65 enrolled 21 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00662506 2023-06-06

Cediranib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

46 enrolled