Clinical Trials

MyeloidOther hematologic neoplasmSarcoma

100 enrolled

Blast Crisis, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Sarcoma, Myeloid

NCT05726383 2026-05-22

Iscador® P (Mistletoe) Immunotherapy for Recurrent Resectable Osteogenic Sarcoma

32 enrolled

Bone Neoplasms, Neoplasm Metastasis, Sarcoma

NCT07049848 2026-05-22

SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma

50 enrolled

NCT07434843 2026-05-22

PEMIGIST

24 enrolled

Gastrointestinal Stromal Tumors

NCT07467772 2026-05-22

Ph 2 Elacestrant in ER Positive Uterine Sarcomas

30 enrolled

GynecologicSarcoma

Adenosarcoma of the uterus, Sarcoma, Endometrial Stromal, Perivascular Epithelioid Cell Neoplasms

NCT07602049 2026-05-22

Cryoablation Plus Camrelizumab for Advanced Soft Tissue Sarcoma

57 enrolled

Sarcoma, Osteosarcoma

NCT03643133 2026-05-19

SARCOME13

60 enrolled

Osteosarcoma, Neoplasms, Bone Tissue

NCT07428993 2026-05-19

Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma

41 enrolled

Osteosarcoma

NCT05457829 2026-05-18

Doxorubicin Hydrochloride Liposome Combined With Irinotecan (AI Regimen) Versus VIT Regimen in the Treatment of Relapsed and Refractory Pediatric Rhabdomyosarcoma: a Prospective, Open-label, Randomized Controlled, Multicenter, Phase II Clinical Study

88 enrolled

Rhabdomyosarcoma

NCT05941325 2026-05-14

A Single-arm, Open-label, Single-center Prospective Study of Fruquintinib Combined With Envafolimab in the Treatment of Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma

Phase 2 Suspended

20 enrolled

NCT07089992 2026-05-14

A Study of Pembrolizumab in People With Ultra-Rare Sarcomas

32 enrolled

Liposarcoma, Sarcoma, Perivascular Epithelioid Cell Neoplasms

NCT05864534 2026-05-13

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

25 enrolled

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT03972930 2026-05-12

Hypofractionated Radiotherapy for Soft Tissue Sarcomas

48 enrolled 10 charts

NCT05694871 2026-05-11

Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma

77 enrolled

Liposarcoma

NCT06898970 2026-05-08

Intratumoral Vusolimogene Oderparepvec (VO) in Combination With Pembrolizumab for Angiosarcoma

18 enrolled

Hemangiosarcoma

NCT07575724 2026-05-08

Comparison of the Effects of Needle Biopsy Tract Resection and Non-resection on Recurrence Rate in Patients With Primary Extremity Sarcoma

3,300 enrolled

NCT07576725 2026-05-08

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidSarcomaThoracic

50 enrolled

Clear-cell metastatic renal cell carcinoma, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Hodgkin Disease, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Sarcoma, Kaposi, Colorectal Neoplasms, Carcinoma, Merkel Cell

NCT01042379 2026-05-06

I-SPY

5,000 enrolled

BreastSarcoma

Pathologic Complete Response, Breast Neoplasms, Hemangiosarcoma, Neoplasms, Triple Negative Breast Neoplasms

NCT03349450 2026-05-06

SPiReL

25 enrolled 18 charts

LymphoidSarcoma

Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Recurrence, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Dendritic Cell Sarcoma, Interdigitating

NCT05985161 2026-05-06

A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

45 enrolled

GenitourinarySarcoma

Wilms Tumor, Neurofibrosarcoma, Rhabdoid Tumor

NCT04807816 2026-05-05

TARSARC

58 enrolled

Leiomyosarcoma, Neoplasm Metastasis, Sarcoma

NCT04200443 2026-05-01

Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma

96 enrolled 15 charts

Leiomyosarcoma, Sarcoma

NCT07560826 2026-05-01

The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma

46 enrolled

Osteosarcoma

NCT04605770 2026-04-30

ALBATROSS

164 enrolled

Phase 2 Enrolling by invitation

NCT07550582 2026-04-30

SAVE-GEJ

40 enrolled

Gastrointestinal Stromal Tumors

NCT07559864 2026-04-30

Comparing Regorafenib Combined With Envafolimab to Physician's Choice in Patients With Metastatic Gastrointestinal Stromal Tumors Harboring KIT Exon 17 Mutations Refractory to Standard Treatment

100 enrolled

Piebaldism, Gastrointestinal Stromal Tumors

NCT05156268 2026-04-27

A Study of Pembrolizumab and Olaparib in People With Endometrial Cancer or Endometrial Carcinosarcoma

26 enrolled

GynecologicSarcoma

Endometrial Carcinosarcoma

NCT07552324 2026-04-27

Study on the Treatment of Double/Triple-hit DLBCL With Chidamide and Lisaftoclax in Combination With Pola-R-CHP

28 enrolled

Dendritic Cell Sarcoma, Interdigitating

NCT00840047 2026-04-24

Methionine PET/CT Studies In Patients With Cancer

503 enrolled

CNSLymphoidSarcoma

Craniopharyngioma, Ependymoma, Hodgkin Disease, Lymphoma, Non-Hodgkin, Medulloblastoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT01871766 2026-04-24

Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

115 enrolled

Rhabdomyosarcoma

NCT05152472 2026-04-24

ATEZOGIST

110 enrolled

Neoplasms, Gastrointestinal Stromal Tumors

NCT07243626 2026-04-24

Efficacy and Safety of Envafolimab Plus Doxorubicin and Ifosfamide for Advanced Soft Tissue Sarcoma

25 enrolled

NCT03414229 2026-04-23

A Study of Epacadostat, an IDO1 Inhibitor, in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

30 enrolled 11 charts

NCT04278781 2026-04-23

AG-120 in People With IDH1 Mutant Chondrosarcoma

6 enrolled

LymphoidSarcoma

Chondrosarcoma, Lymphoma, Follicular

NCT04332874 2026-04-23

A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

30 enrolled

Sarcoma, Dermatofibrosarcoma, Sarcoma, Alveolar Soft Part, Histiocytoma, Malignant Fibrous

NCT04095208 2026-04-21

CONGRATS

68 enrolled

Tertiary Lymphoid Structures, Neoplasm Metastasis, Neoplasms, Sarcoma

NCT04968106 2026-04-21

TORNADO

66 enrolled

NCT04028063 2026-04-20

Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas

65 enrolled

NCT02713269 2026-04-17

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

60 enrolled

Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasms, Unknown Primary, Sarcoma, Spinal Cord Compression, Thyroid Neoplasms

NCT05019703 2026-04-17

Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study

40 enrolled

Osteosarcoma

NCT07283731 2026-04-17

Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma

20 enrolled

Neoplasm Metastasis, Sarcoma

NCT04668300 2026-04-15

DOSa

75 enrolled

Hemangiosarcoma, Liposarcoma, Osteosarcoma

NCT06638931 2026-04-15

ANTARES

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther solid neoplasmSarcomaThoracic

28 enrolled

Urachal adenocarcinoma, Urachal cancer, Fibrolamellar hepatocellular carcinoma, Secretory breast carcinoma, Carcinoma, Ovarian Epithelial, Adrenal Gland Neoplasms, Anus Neoplasms, Biliary Tract Neoplasms, Carcinosarcoma, Carcinoma, Adenoid Cystic, Fallopian Tube Neoplasms, Fibrosarcoma, Gallbladder Neoplasms, Granulosa Cell Tumor, Hemangiosarcoma, Leiomyosarcoma, Mesothelioma, Neuroblastoma, Parathyroid Neoplasms, Penile Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Thyroid Neoplasms, Trophoblastic Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Hepatoblastoma, Endodermal Sinus Tumor, Neuroectodermal Tumors, Primitive, Cholangiocarcinoma, Sertoli-Leydig Cell Tumor, Neurofibrosarcoma, Hemangioblastoma, Neuroendocrine Tumors

NCT05879185 2026-04-13

A Study of XmAb23104 in People With Sarcoma

Phase 2 Terminated

6 enrolled 9 charts