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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other solid neoplasm 57Thoracic 1

Conditions

Carcinoma, Non-Small-Cell Lung 861Lung Neoplasms 586Small Cell Lung Carcinoma 169Colorectal Neoplasms 134Breast Neoplasms 108Melanoma 101Neoplasms 91Ovarian Neoplasms 90Neoplasm Metastasis 84Pancreatic Neoplasms 75Squamous Cell Carcinoma of Head and Neck 69Stomach Neoplasms 60Carcinoma, Renal Cell 56Head and Neck Neoplasms 55Esophageal Neoplasms 49Triple Negative Breast Neoplasms 48Endometrial Neoplasms 47Prostatic Neoplasms 46Uterine Cervical Neoplasms 41Urinary Bladder Neoplasms 40Colonic Neoplasms 40Mesothelioma 38Carcinoma, Hepatocellular 36Mesothelioma, Malignant 34Brain Neoplasms 31Adenocarcinoma of Lung 29Sarcoma 28Carcinoma, Transitional Cell 28Lung Diseases 24Gastrointestinal Neoplasms 24

Interventions

olaparib 1adagrasib 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Advanced Solid Tumor × Thoracic × 90 days × Clear all
NCT06130254 2026-04-09

Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers

M.D. Anderson Cancer Center

Phase 1 Terminated
1 enrolled
Other solid neoplasmThoracic

Advanced Solid Tumor

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