Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Recruiting 1Completed 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 13Breast 3Thoracic 2Sarcoma 2Dermatologic 1

Conditions

Carcinoma, Non-Small-Cell Lung 10Breast Neoplasms 3Neoplasm Metastasis 2Mesothelioma, Malignant 2Melanoma 2Lung Neoplasms 2Colorectal Neoplasms 2Brain Neoplasms 2Small Cell Lung Carcinoma 1Mesothelioma 1Lymphoma, Non-Hodgkin 1Lymphoma 1Glioma 1Glioblastoma 1

Interventions

Radiosurgery 27Radiotherapy 17Magnetic Resonance Spectroscopy 14Erlotinib Hydrochloride 14Bevacizumab 13Pemetrexed 10Carboplatin 10pembrolizumab 9Gefitinib 9osimertinib 8icotinib 7Temozolomide 7Nivolumab 6Specimen Handling 5Paclitaxel 5Spermine Synthase 4Mental Status and Dementia Tests 4Ipilimumab 4Drug Therapy 4Cisplatin 4atezolizumab 3alectinib 3aflutinib 3Radiation 3Immunotherapy 3Fluorodeoxyglucose F18 3regorafenib 2paclitaxel-Angiopep-2 conjugate 2motexafin gadolinium 2epothilone B 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Brain Neoplasms × abemaciclib × Thoracic × Clear all
NCT06810544 2026-04-13

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Tango Therapeutics, Inc.

Phase 1/2 Recruiting
191 enrolled
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Glioma, Lung Neoplasms

NCT02308020 2020-12-19

A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain

Eli Lilly and Company

Phase 2 Completed
162 enrolled 25 charts
BreastCNSDermatologicThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma

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