Clinical Trials Browser

NCT05538130 2026-06-05

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

Phase 1 Recruiting

124 enrolled

CNSDermatologicHead & NeckThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioma, Melanoma, Neoplasms, Thyroid Neoplasms

NCT06253871 2026-06-04

A Phase 1/1b Study of IAM1363 in HER2 Cancers

Phase 1 Recruiting

383 enrolled

BreastCNSGastrointestinalThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Neoplasms, Stomach Neoplasms

NCT06673329 2026-05-13

Brodalumab in the Treatment of Immune-Related Adverse Events

Phase 1 Recruiting

11 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms

Clinical Trials

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

A Phase 1/1b Study of IAM1363 in HER2 Cancers

Brodalumab in the Treatment of Immune-Related Adverse Events

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

LIMITLESS

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.

DURABLE

Bevacizumab Plus FSRT Versus Hippocampus-Avoidant WBRT in Lung Adenocarcinoma With Extensive Brain Metastases

ACROP

Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance

CyberChallenge

MOMENTUM

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer

REPOSE

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

CAMPERR

7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)

WAYWIN103

Elimination of PTV Margins Based on MRI-guided Adaptive Stereotactic Radiotherapy for Non-small Cell Lung Cancer With Brain Metastasis

Stereotactic Magnetic Resonance Guided Radiation Therapy

TROPICAL-1

Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers

SHARP

JYP0322

SPARTA

Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases

Better Brain

Cadonilimab Combined With Stereotactic Radiotherapy as Second-line Treatment for Brain Metastases

Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Stable Brain Metastasis

SRT Combined With Anlotinib for the Treatment of Brain Metastases From Non-small Cell Lung Cancer

Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors

SILMET

The Effects of Using Different Anesthetics on the Prognosis of Primary Tumors and Its Mechanism of Action

A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Advanced Solid Tumors

Hippocampal-Sparing Prophylactic Cranial Irradiation in Pathologically Nodal Positive Non-Small-Cell Lung Cancer

A Study to Evaluate the Efficacy of Osimertinib With Early Intervention SRS Treatment Compared to the Continuation of Osimertinib Alone, in Patients With EGFR Mutated NSCLC and Asymptomatic Brain Metastases