Announcements Trials
Browse Landscape

Phase

Phase 2 2Phase 1/2 1Phase 1 1

Status

Completed 4

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4

Conditions

Small Cell Lung Carcinoma 76Lung Neoplasms 39Carcinoma, Non-Small-Cell Lung 11Ovarian Neoplasms 5Neoplasm Metastasis 5Carcinoma, Small Cell 4Uterine Cervical Neoplasms 2Recurrence 2Pancreatic Neoplasms 2Neoplasms 2Extensive Stage Small Cell Lung Cancer 2Esophageal Neoplasms 2Carcinoma, Neuroendocrine 2Adenocarcinoma, Bronchiolo-Alveolar 2Adenocarcinoma of Lung 2Triple Negative Breast Neoplasms 1Stomach Neoplasms 1SCLC, Extensive Stage 1SCLC 1Radiation Injuries 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Neoplasms, Unknown Primary 1Melanoma 1Lymphoma, T-Cell, Cutaneous 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1

Interventions

Cisplatin 6Etoposide 5Topotecan 4Carboplatin 4Pemetrexed 3Gemcitabine 3belinostat 2Temozolomide 2RRx-001 2vosaroxin 1vinflunine 1veliparib 1taxane 1sagopilone 1sacituzumab govitecan 1pembrolizumab 1lurtotecan 1liposomal doxorubicin 1enzalutamide 1bemiparin 1belotecan 1atezolizumab 1apalutamide 1alvocidib 1abiraterone 1Vinorelbine 1Tomography, X-Ray Computed 1Sorafenib 1Rhenium 1Radiation 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Carcinoma, Small Cell × Topotecan × Thoracic × Clear all
NCT03554473 2025-05-09

M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
37 enrolled 19 charts
Thoracic

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT00466232 2015-12-16

Phase I Study of Weekly Topotecan in Combination With Sorafenib in Treatment of Relapsed Small Cell Lung Cancer

HealthPartners Institute

Phase 1 Completed
16 enrolled
Thoracic

Lung Neoplasms, Carcinoma, Small Cell

NCT00305942 2013-01-31

Topotecan and Carboplatin in the First-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer

SCRI Development Innovations, LLC

Phase 2 Completed
61 enrolled 9 charts
Thoracic

Lung Neoplasms, Carcinoma, Small Cell

NCT00294190 2012-12-10

Higher Dose Weekly Topotecan In The Treatment Of Patients With Extensive Stage Small-Cell Lung Cancer

SCRI Development Innovations, LLC

Phase 2 Completed
38 enrolled
Thoracic

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

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