Announcements Trials
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Phase

Phase 3 1Phase 1 1

Status

Completed 2No longer available 1

Sponsor Class

INDUSTRY 3

Study Type

Interventional 2Expanded_access 1

Sponsor

Cancer Type

Thoracic 3Gastrointestinal 1

Conditions

Carcinoma, Non-Small-Cell Lung 22Lung Neoplasms 9Carcinoma 3Carcinoma, Squamous Cell 2Carcinoma, Large Cell 2Adenocarcinoma 2ALK-positive Advanced NSCLC 2Sexual Dysfunction, Physiological 1Neoplasms 1NSCLC 1Lymphoma, Large-Cell, Anaplastic 1Gastrointestinal Neoplasms 1Eunuchism 1Erectile Dysfunction 1Disease Progression 1Breast Neoplasms 1Brain Neoplasms 1ALK-positive NSCLC 1ALK+ Advanced NSCLC 1

Interventions

Carboplatin 24Pemetrexed 18Cisplatin 17Paclitaxel 14pembrolizumab 13Gemcitabine 8osimertinib 7durvalumab 6Docetaxel 6Nivolumab 5Erlotinib Hydrochloride 5130-nm albumin-bound paclitaxel 5capmatinib 3brigatinib 3anlotinib 3Gefitinib 3Drug Therapy 3vosaroxin 2volociximab 2sintilimab 2pralsetinib 2ensartinib 2atezolizumab 2aflibercept 2Surgical Procedures, Operative 2Radiotherapy, Intensity-Modulated 2Radiotherapy 2Radiation 2Oncolytic Virotherapy 2Ipilimumab 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Carcinoma × brigatinib × Thoracic × Clear all
NCT03420742 2023-01-27

A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid Tumors

Takeda

Phase 1 Completed
24 enrolled 17 charts
Thoracic

Carcinoma, Lung Neoplasms, Neoplasms

NCT02737501 2021-08-20

ALTA-1L

Takeda

Phase 3 Completed
275 enrolled 23 charts 1 FDA
Thoracic

Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Carcinoma, Large Cell

NCT02784158 2018-02-06

An Expanded Access Study of Brigatinib for Patients With ALK-positive Advanced Non-Small Cell Lung Cancer

Takeda

No longer available
Thoracic

Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Carcinoma, Large Cell

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