Clinical Trials

GastrointestinalGynecologicThoracic

26 enrolled

Carcinoma, Uterine Cervical Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT02592577 2025-12-09

MAGE A10ᶜ⁷⁹⁶T for Advanced NSCLC

28 enrolled

Phase 1 Active not recruiting

Carcinoma, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT04603287 2025-09-26

A Study of SI-B001, an EGFR/HER3 Bispecific Antibody, in Locally Advanced or Metastatic Epithelial Tumors

60 enrolled

GastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Colorectal Neoplasms

NCT02185690 2025-08-21

MEK162

13 enrolled 11 charts

Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06069570 2025-03-05

Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases

Phase 1 Recruiting

48 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT04862780 2025-02-10

(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC

177 enrolled

Adenocarcinoma, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT05241873 2025-02-10

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

103 enrolled

CNSThoracic

Adenocarcinoma, Brain Neoplasms, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT02164461 2024-05-20

Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer

DermatologicHead & NeckThoracic

12 enrolled 18 charts

GynecologicThoracic

Adenocarcinoma, Carcinoma, Carcinoma, Squamous Cell, Uterine Cervical Diseases, Uterine Cervical Neoplasms, Genital Diseases, Female, Genital Neoplasms, Female, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Urogenital Neoplasms, Uterine Diseases, Uterine Neoplasms, Carcinoma, Adenosquamous, Carcinoma, Small Cell, Neoplasms, Squamous Cell, Small Cell Lung Carcinoma

NCT06307093 2024-03-12

Study Comparing the Pharmacokinetics, Safety, and Efficacy of RPH-075 and Keytruda® in Patients With Malignant Neoplasms

Phase 1 Unknown

90 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Lung Neoplasms, Melanoma, Neoplasms

NCT05375825 2024-02-02

Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin

Phase 1 Withdrawn

MyeloidOther solid neoplasmThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Mesothelioma, Malignant, Carcinoma, Pleural Effusion, Malignant

NCT05969041 2024-01-18

MYE Symphony

Phase 1 Recruiting

48 enrolled

BreastGastrointestinalGynecologicThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT05498597 2023-10-19

AMT-151 in Patients With Selected Advanced Solid Tumours

Phase 1 Unknown

30 enrolled

BreastGynecologicOther solid neoplasmThoracic

Adenocarcinoma of Lung, Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Carcinoma, Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05153408 2023-06-18

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

20 enrolled

Adenocarcinoma, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT03420742 2023-01-27

A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid Tumors

24 enrolled 17 charts

Carcinoma, Lung Neoplasms, Neoplasms

NCT02437916 2022-11-08

Safety Study of AMG 228 to Treat Solid Tumors

DermatologicGastrointestinalHead & NeckThoracic

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Melanoma, Neoplasms, Colorectal Neoplasms

NCT04596033 2022-07-15

TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapy

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

49 enrolled

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasms, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma

NCT01587703 2020-03-16

A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of GSK525762 in Subjects With NUT Midline Carcinoma (NMC) and Other Cancers

196 enrolled 78 charts

CNSPlasma cellThoracic

Carcinoma, Multiple Myeloma, Neoplasms, Neuroblastoma, Small Cell Lung Carcinoma

NCT00097903 2020-03-12

Trial of Oral Karenitecin in Patients With Solid Tumors and Lung Cancer

32 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT00793208 2019-04-12

Immunization of Patients With Non Small Cell Lung Cancer (NSCLC)

1 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00926640 2018-10-19

A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers

28 enrolled

EndocrineThoracic

Carcinoma, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT00599755 2018-01-16

Phase I Imaging Study Evaluating Gem/Cis or Gem/Carbo for Participants With Non-Small Cell Lung Cancer (MK-0000-083 AM3)

68 enrolled 12 charts

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT00654758 2017-11-21

A Phase 1b Study With Volociximab in Combination With Carboplatin and Paclitaxel in First-line, Advanced Non-Small Cell Lung Cancer (NSCLC)

33 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT00506051 2016-08-25

ZD6474(Vandetanib) + Alimta Combo Study

21 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00129012 2016-02-25

Self-Gated Breath-Hold Technique for Helical Tomotherapy in Patients With Non-Small Cell Lung Cancer

30 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT00441337 2015-02-20

MDX1106-01

DermatologicGastrointestinalGenitourinaryThoracic

39 enrolled 28 charts

Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Prostatic Neoplasms, Recurrence, Colorectal Neoplasms

NCT00243347 2013-10-17

The Effects of AZD2171 in Patients With Non-Small Cell Lung Cancer or Head & Neck Cancer

19 enrolled 7 charts

Head & NeckThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms

NCT00666692 2012-04-27

A Phase 1b Study With Volociximab in Combination With Carboplatin, Paclitaxel, and Bevacizumab in First-line, Advanced Non-small Cell Lung Cancer (NSCLC)

7 enrolled