Announcements Trials
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Phase

Phase 1 2

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gynecologic 8Thoracic 2Gastrointestinal 2Breast 2Sarcoma 1Head & Neck 1Genitourinary 1Endocrine 1Dermatologic 1CNS 1

Conditions

Carcinoma, Non-Small-Cell Lung 41Colorectal Neoplasms 15Lung Neoplasms 12Ovarian Neoplasms 6Stomach Neoplasms 5Pancreatic Neoplasms 5Neoplasms 5Rectal Neoplasms 4Neoplasm Metastasis 4Melanoma 4Colonic Neoplasms 4Carcinoma, Renal Cell 4Triple Negative Breast Neoplasms 3Squamous Cell Carcinoma of Head and Neck 3Small Cell Lung Carcinoma 3Recurrence 3Mesothelioma 3Carcinoma, Pancreatic Ductal 3Peritoneal Neoplasms 2Fallopian Tube Neoplasms 2Esophageal Neoplasms 2Endometrial Neoplasms 2Breast Neoplasms 2Vipoma 1Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Thyroid Neoplasms 1Spinocerebellar Degenerations 1Somatostatinoma 1Skin Neoplasms 1

Interventions

pembrolizumab 7Carboplatin 5Cisplatin 4Drug Therapy 3Taxes 2Specimen Handling 2SS1(dsFv)PE38 2Polymerase Chain Reaction 2Paclitaxel 2Oxaliplatin 2Nivolumab 2Magnetic Resonance Spectroscopy 2Leucovorin 2Hyperthermic Intraperitoneal Chemotherapy 2Gene Expression Profiling 2Fluorouracil 2Doxorubicin 2Cyclophosphamide 2130-nm albumin-bound paclitaxel 2tremelimumab 1tocilizumab 1tinostamustine 1sodium thiosulfate 1selinexor 1rucaparib 1olaparib 1motexafin lutetium 1liposomal doxorubicin 1fludarabine 1eribulin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Fallopian Tube Neoplasms × Oxaliplatin × Thoracic × Clear all
NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

M.D. Anderson Cancer Center

Phase 1 Terminated
221 enrolled
BreastDermatologicGenitourinaryGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT02658214 2020-08-20

Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors

AstraZeneca

Phase 1 Completed
32 enrolled
BreastGastrointestinalGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Carcinoma, Pancreatic Ductal, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

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