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Phase

Phase 2 2Phase 1/2 2Phase EARLY_PHASE1 1

Status

Completed 4Terminated 1

Sponsor Class

OTHER 15INDUSTRY 5

Study Type

Interventional 5

Sponsor

Cancer Type

Gastrointestinal 7Head & Neck 6Thoracic 5Genitourinary 5Other hematologic neoplasm 3Gynecologic 2Sarcoma 1Plasma cell 1NET 1Lymphoid 1Endocrine 1Dermatologic 1Breast 1

Conditions

Carcinoma, Non-Small-Cell Lung 2729Lung Neoplasms 945Small Cell Lung Carcinoma 447Neoplasms 419Colorectal Neoplasms 409Breast Neoplasms 355Melanoma 332Ovarian Neoplasms 316Neoplasm Metastasis 281Pancreatic Neoplasms 252Squamous Cell Carcinoma of Head and Neck 232Stomach Neoplasms 227Carcinoma, Renal Cell 214Triple Negative Breast Neoplasms 190Head and Neck Neoplasms 178Prostatic Neoplasms 152Esophageal Neoplasms 149Endometrial Neoplasms 145Uterine Cervical Neoplasms 139Urinary Bladder Neoplasms 132Mesothelioma 115Carcinoma 106Colonic Neoplasms 104Carcinoma, Hepatocellular 104Sarcoma 99Carcinoma, Transitional Cell 99Kidney Neoplasms 74Mesothelioma, Malignant 72Cholangiocarcinoma 67Liver Neoplasms 66

Interventions

fluoromisonidazole 1TH 302 13-fluoro-2-(4-((2-nitro-1H-imidazol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)propan-1-ol 13-(4-(2-fluoroethoxy)phenyl)-2-(3-methyl-2-(4-((2-sulfamoylbenzo(d)thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)butanamido)propanoic acid 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
INDUSTRY × Hypoxia × Thoracic × Clear all
NCT02454842 2023-01-12

TH-4000

Rain Oncology Inc

Phase 2 Terminated
21 enrolled
Thoracic

Hypoxia, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell

NCT00743379 2015-05-07

Dose-Escalation Study of TH-302 in Combination With A) Gemcitabine or B) Docetaxel or C) Pemetrexed to Treat Advanced Solid Tumors

Threshold Pharmaceuticals

Phase 1/2 Completed
71 enrolled
GastrointestinalGenitourinaryThoracic

Hypoxia, Carcinoma, Non-Small-Cell Lung, Pancreatic Neoplasms, Prostatic Neoplasms

NCT01075399 2013-08-30

HX4-200

Siemens Molecular Imaging

Phase 2 Completed
50 enrolled 7 charts
GastrointestinalGynecologicHead & NeckThoracic

Hypoxia, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Rectal Neoplasms

NCT01213030 2012-09-25

Clinical Evaluation of the New Hypoxia Imaging Agent HX4

Siemens Molecular Imaging

Phase 1/2 Completed
12 enrolled
GastrointestinalHead & NeckThoracic

Hypoxia, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms

NCT00884520 2010-03-16

VM4-037

Siemens Molecular Imaging

Phase EARLY_PHASE1 Completed
16 enrolled
GastrointestinalGenitourinaryHead & NeckThoracic

Hypoxia, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms

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