Clinical Trials

GastrointestinalGynecologicOther solid neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06885697 2026-06-05

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Phase 1 Recruiting

100 enrolled

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

NCT07063745 2026-06-05

MountainTAP-29

Phase 2/3 Recruiting

590 enrolled

Phase NA Not yet recruiting

Lung Neoplasms

NCT07127874 2026-06-05

A Study of PHN-012 in Patients With Advanced Solid Tumors

Phase 1 Recruiting

165 enrolled

GastrointestinalThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms

NCT07176000 2026-06-05

Tailored Patient Navigation to Improve the Uptake of Lung Cancer Screening in Tribal Communities in Western Washington State, SACRED LUNGS Trial

237 enrolled

Lung Neoplasms

NCT07353957 2026-06-05

Study to Investigate Petosemtamab in Adults With Metastatic Non-Small Cell Lung Cancer

Phase 2 Recruiting

180 enrolled

Lung Neoplasms

NCT07513818 2026-06-05

IMPULSION

20,000 enrolled

Lung Neoplasms, Smoking Cessation

NCT07564960 2026-06-05

Social Optimization Study

30 enrolled

Phase 2 Not yet recruiting

Lung Neoplasms

NCT07629960 2026-06-05

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

Phase 1/2 Recruiting

265 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07630168 2026-06-05

TIMED

238 enrolled

Head & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Lung Neoplasms

NCT07630246 2026-06-05

PAIR-LUNG

Not yet recruiting

140 enrolled

Adenocarcinoma of Lung, Lung Neoplasms

NCT00238628 2026-06-04

A Phase I/II Study of Bexarotene in Combination With ZD1839 (IRESSA®) in the Treatment of Non-Small Cell Lung Cancer

Phase 1/2 Completed

6 enrolled

Lung Neoplasms

NCT05920356 2026-06-04

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

750 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT06003335 2026-06-04

Increasing Physical Activity Through Personalised Motivational Messaging to Improve Cognitive Function in Lung Cancer Survivors

Phase NA Completed

124 enrolled

Lung Neoplasms, Motor Activity

NCT07222566 2026-06-04

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

1,410 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT07476287 2026-06-04

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

Phase 2 Recruiting

40 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT07554677 2026-06-04

PReFACe

30 enrolled

Phase 3 Not yet recruiting

Lung Neoplasms, Motor Activity

NCT07625644 2026-06-04

Evaluate BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer

550 enrolled

Lung Neoplasms, Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT07626177 2026-06-04

Association Between Screening Behaviors and Lung Cancer Spectrum

Recruiting

5,390 enrolled

Phase NA Not yet recruiting

Lung Neoplasms

NCT07627022 2026-06-04

APPAREL

32 enrolled

Phase 2 Active not recruiting

Lung Neoplasms, Motor Activity

NCT01451853 2026-06-03

SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss

Phase 2 Withdrawn

Head & NeckThoracic

Ototoxicity, Deafness, Head and Neck Neoplasms, Lung Neoplasms, Tinnitus, Hearing Loss

NCT02465060 2026-06-03

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

6,452 enrolled 1 FDA

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmPlasma cellThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioma, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Melanoma, Multiple Myeloma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Uterine Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

NCT02676050 2026-06-03

DUAL

Phase EARLY_PHASE1 Terminated

5 enrolled

Phase NA Active not recruiting

Lung Neoplasms

NCT03881098 2026-06-03

The Lung PCA: A Multi-Dimensional Atlas of Pulmonary Premalignancy

240 enrolled

Carcinoma, Squamous Cell, Lung Neoplasms, Smoking

NCT04181060 2026-06-03

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

300 enrolled

Lung Neoplasms

NCT04267848 2026-06-03

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

1,210 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05642572 2026-06-03

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

Phase 2 Recruiting

66 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05984680 2026-06-03

COPD Care Pathway Among Patients With Cancer

Completed

101 enrolled

Head & NeckThoracic

Head and Neck Neoplasms, Lung Neoplasms, Pulmonary Disease, Chronic Obstructive

NCT06040541 2026-06-03

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

Phase 1 Recruiting

604 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06096844 2026-06-03

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

304 enrolled

Lung Neoplasms

NCT06119581 2026-06-03

SUNRAY-01

1,264 enrolled

Phase 2 Active not recruiting

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT06194448 2026-06-03

NEOLA

76 enrolled

Lung Neoplasms

NCT06498635 2026-06-03

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

306 enrolled

DermatologicHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06897735 2026-06-03

EDDIS-a1

Phase 1 Terminated

4 enrolled

Lung Neoplasms, Melanoma, Mouth Neoplasms

NCT07169617 2026-06-03

Testing the SurVaxM Vaccine for Lung Cancer Prevention

Phase 2 Not yet recruiting

80 enrolled

Lung Neoplasms

NCT07552584 2026-06-03

BREATHE

1,000 enrolled

Disease, Lung Neoplasms, Pulmonary Disease, Chronic Obstructive

NCT07623473 2026-06-03

NIMBLE

Recruiting

1,800 enrolled

Solitary Pulmonary Nodule, Disease, Lung Neoplasms

NCT07624318 2026-06-03

ALINEAR

Not yet recruiting

3,400 enrolled

Phase 1 Active not recruiting

Lung Neoplasms

NCT04514497 2026-06-02

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer

29 enrolled 25 charts

EndocrineGastrointestinalThoracic

Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT04881045 2026-06-02

Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.

Phase 1 Completed

29 enrolled

GynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms

NCT05132075 2026-06-02

KontRASt-02

Phase 3 Active not recruiting

95 enrolled

BreastDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidOther hematologic neoplasmSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05334069 2026-06-02

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Recruiting

2,000 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Esophageal Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05968898 2026-06-02

ARCADES

300 enrolled