Clinical Trials

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04479306 2026-04-16

Osimertinib in Combination With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung Cancer

Phase 1 Completed

37 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04595422 2026-04-16

Educating Smokers About Lung Cancer Screening Using Tobacco Quitlines

800 enrolled

Lung Neoplasms

NCT04701476 2026-04-16

TATE and Pembrolizumab (MK3475) in mCRC and NSCLC

110 enrolled

GastrointestinalThoracic

Lung Neoplasms, Colorectal Neoplasms

NCT04783168 2026-04-16

AIRTECH

240 enrolled

Lung Neoplasms

NCT04789681 2026-04-16

Canakinumab for the Prevention of Lung Cancer, the Can-Prevent-Lung Trial

50 enrolled

Phase 3 Active not recruiting

Lung Neoplasms

NCT05450692 2026-04-16

LATIFY

594 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05817110 2026-04-16

CREATE

Active not recruiting

712 enrolled

Phase NA Not yet recruiting

Lung Neoplasms

NCT06538636 2026-04-16

PASI

23,520 enrolled

Lung Neoplasms

NCT07100080 2026-04-16

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Phase 2/3 Recruiting

596 enrolled

Phase NA Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07177846 2026-04-16

LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Protocol for Patients Living With Metastatic Lung Cancer

80 enrolled

Lung Neoplasms

NCT07185997 2026-04-16

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

Phase 3 Recruiting

480 enrolled

Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Respiratory Tract Neoplasms

NCT07220096 2026-04-16

Registry Trial and Needs Assessment of Patients With Young-onset Lung Cancer: Impact of a Dedicated Care Program on Patient Experience and Outcomes

75 enrolled

Lung Neoplasms

NCT07532057 2026-04-16

PR-LUNGCA-2019

Phase NA Completed

30 enrolled

Lung Neoplasms, Neoplasms, Small Cell Lung Carcinoma

NCT01630733 2026-04-15

ENSPIRIT

Phase 3 Completed

664 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT02596490 2026-04-15

Couple-Based Meditation for Metastatic Lung Cancer Patients and Their Partners

300 enrolled

Phase 2/3 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03637816 2026-04-15

Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung Cancer

25 enrolled

Anorexia, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03655015 2026-04-15

Patient-derived Organoid Model and Circulating Tumor Cells for Treatment Response of Lung Cancer

150 enrolled

Phase NA Active not recruiting

Lung Neoplasms

NCT03731585 2026-04-15

Online Psychosocial Intervention in Improving Social Well-Being and Support in Women With Stage I-IV Non-small Cell Lung Cancer Undergoing Treatment

70 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03948100 2026-04-15

Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers

400 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Lung Neoplasms

NCT04614103 2026-04-15

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

170 enrolled

Phase NA Active not recruiting

Bronchial Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms

NCT05144542 2026-04-15

Risk and Benefits of Electronic Cigarettes to Older Smokers at High Risk for Lung Cancer

140 enrolled

Phase 2 Active not recruiting

Lung Neoplasms

NCT05470595 2026-04-15

LCNEC-ALPINE

67 enrolled

EndocrineThoracic

Lung Neoplasms, Carcinoma, Neuroendocrine

NCT05704634 2026-04-15

A Phase Ib Study to Evaluate the Safety and Preliminary Efficacy of IL6-receptor Antibody Sarilumab in Combination With antiPD1 Antibody Cemiplimab for Patients With Non-small Cell Lung Cancer.

Phase 1 Active not recruiting

56 enrolled

Lung Neoplasms

NCT06096844 2026-04-15

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Phase 3 Recruiting

304 enrolled

Phase 3 Active not recruiting

Lung Neoplasms

NCT06151574 2026-04-15

Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment

416 enrolled

Lung Neoplasms

NCT06343402 2026-04-15

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

Phase 1 Recruiting

350 enrolled

Phase 1 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06685718 2026-04-15

A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer

33 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06688422 2026-04-15

INSPIRE-CRT

100 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pneumonia

NCT07288034 2026-04-15

Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

535 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07458347 2026-04-15

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

Phase 1 Recruiting

145 enrolled

Biliary Tract Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT00001823 2026-04-14

Evaluation for NCI Surgery Branch Clinical Research Protocols

DermatologicGastrointestinalGenitourinaryThoracic

7,000 enrolled

Urinary Bladder Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Colorectal Neoplasms

NCT00034216 2026-04-14

Collection of Blood From Patients With Cancer

BreastGastrointestinalGenitourinaryThoracic

1,750 enrolled

Breast Neoplasms, Colonic Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Prostatic Neoplasms

NCT00340405 2026-04-14

Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, China

Completed

9,759 enrolled

Lung Neoplasms

NCT01441089 2026-04-14

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

BreastGenitourinaryGynecologicLymphoidThoracic

1,100 enrolled

Breast Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms

NCT06026111 2026-04-14

ENHANCE

30 enrolled

Phase 1 Active not recruiting

Lung Neoplasms

NCT06091930 2026-04-14

A Study to Test Different Doses of BI 765049 Alone and in Combination With Ezabenlimab in Asian People With Advanced Cancer (Solid Tumours) Positive for B7-H6

97 enrolled

GastrointestinalHead & NeckThoracic

Gastrointestinal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07073898 2026-04-14

UG3 Pilot Clinical Trial

Phase NA Completed

65 enrolled