Announcements Trials
Browse Landscape

Phase

Phase 1 2

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 4Breast 3Thoracic 2Dermatologic 2

Conditions

Carcinoma, Non-Small-Cell Lung 916Lung Neoplasms 621Small Cell Lung Carcinoma 170Colorectal Neoplasms 133Melanoma 109Breast Neoplasms 107Neoplasms 98Ovarian Neoplasms 94Neoplasm Metastasis 90Pancreatic Neoplasms 76Squamous Cell Carcinoma of Head and Neck 70Stomach Neoplasms 60Carcinoma, Renal Cell 58Head and Neck Neoplasms 55Esophageal Neoplasms 51Endometrial Neoplasms 51Triple Negative Breast Neoplasms 50Prostatic Neoplasms 47Uterine Cervical Neoplasms 44Colonic Neoplasms 42Urinary Bladder Neoplasms 41Mesothelioma 40Carcinoma, Hepatocellular 38Mesothelioma, Malignant 37Brain Neoplasms 34Sarcoma 29Carcinoma, Transitional Cell 29Adenocarcinoma of Lung 28Lung Diseases 26Disease 26

Interventions

sapanisertib 1Spinal Puncture 1Specimen Handling 1Nivolumab 1Magnetic Resonance Spectroscopy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Meningeal Neoplasms × Thoracic × 90 days × Clear all
NCT04250545 2026-05-26

Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

National Cancer Institute (NCI)

Phase 1 Active not recruiting
22 enrolled 14 charts
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Meningeal Neoplasms

NCT03025256 2026-05-05

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

M.D. Anderson Cancer Center

Phase 1 Recruiting
75 enrolled
DermatologicThoracic

Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Meningeal Neoplasms, Nevus

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