Announcements Trials
Browse Landscape

Phase

Phase 1 3Phase NA 1Phase 2 1

Status

Recruiting 2Active not recruiting 2Terminated 1

Sponsor Class

OTHER 4NIH 1

Study Type

Interventional 5Observational 1

Sponsor

Cancer Type

CNS 15Breast 7Thoracic 5Other hematologic neoplasm 5Lymphoid 4Dermatologic 2

Conditions

Carcinoma, Non-Small-Cell Lung 5756Lung Neoplasms 3723Small Cell Lung Carcinoma 1021Breast Neoplasms 668Neoplasms 615Colorectal Neoplasms 560Melanoma 479Ovarian Neoplasms 435Neoplasm Metastasis 431Pancreatic Neoplasms 386Stomach Neoplasms 332Carcinoma, Renal Cell 312Adenocarcinoma of Lung 309Squamous Cell Carcinoma of Head and Neck 306Head and Neck Neoplasms 294Prostatic Neoplasms 285Mesothelioma, Malignant 281Esophageal Neoplasms 266Mesothelioma 244Colonic Neoplasms 225Brain Neoplasms 217Urinary Bladder Neoplasms 212Triple Negative Breast Neoplasms 211Uterine Cervical Neoplasms 209Endometrial Neoplasms 175Sarcoma 171Carcinoma, Hepatocellular 159NSCLC 136Carcinoma 128Kidney Neoplasms 127

Interventions

Spinal Puncture 2sapanisertib 1Specimen Handling 1Phlebotomy 1Nivolumab 1Magnetic Resonance Spectroscopy 1Afatinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × Meningeal Neoplasms × Thoracic × Clear all
NCT04250545 2026-05-26

Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

National Cancer Institute (NCI)

Phase 1 Active not recruiting
22 enrolled 14 charts
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Meningeal Neoplasms

NCT03025256 2026-05-05

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

M.D. Anderson Cancer Center

Phase 1 Recruiting
75 enrolled
DermatologicThoracic

Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Meningeal Neoplasms, Nevus

NCT05305365 2025-12-23

Study Assessing QBS72S For Treating Brain Metastases

Stanford University

Phase 2 Active not recruiting
21 enrolled
BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms, Meningeal Neoplasms

NCT05257967 2025-02-11

CSF Analysis in EGFR Mutant Non-Small Cell Lung Cancer With Leptomeningeal Disease

British Columbia Cancer Agency

Phase NA Recruiting
10 enrolled
CNSThoracic

Carcinoma, Non-Small-Cell Lung, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT03711422 2022-06-14

Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC

National Cancer Centre, Singapore

Phase 1 Terminated
2 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Meningeal Neoplasms

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