Announcements Trials
Browse Landscape

Phase

Phase 2 2Phase 1 2

Status

Terminated 3Withdrawn 1

Sponsor Class

INDUSTRY 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4Other solid neoplasm 4

Conditions

Mesothelioma, Malignant 4Carcinoma, Non-Small-Cell Lung 4Lung Neoplasms 3Pancreatic Neoplasms 2Mesothelioma 2Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Thyroid Neoplasms 1Stomach Neoplasms 1Rectal Neoplasms 1Prostatic Neoplasms 1Ovarian Neoplasms 1Neoplasms, Mesothelial 1Multiple Myeloma 1Melanoma 1Lymphoma 1Hematologic Neoplasms 1Glioma 1Esophageal Neoplasms 1Endometrial Neoplasms 1Colorectal Neoplasms 1Colonic Neoplasms 1Carcinoma, Renal Cell 1Carcinoma, Hepatocellular 1Breast Neoplasms 1Adenoma 1Adenocarcinoma of Lung 1

Interventions

Cisplatin 57Pemetrexed 46pembrolizumab 18Nivolumab 15Carboplatin 15Gemcitabine 14Cyclophosphamide 13Radiotherapy 10Drug Therapy 9atezolizumab 8Platinum 7Ipilimumab 7Doxorubicin 7durvalumab 61,2-diaminocyclohexaneplatinum II citrate 6tremelimumab 5sodium thiosulfate 5Vinorelbine 5Radiotherapy, Intensity-Modulated 5Interleukin-2 5Chemotherapy, Adjuvant 5Cerebral Decortication 5sargramostim 4fludarabine 4defactinib 4aldesleukin 4tumor necrosis factor-alpha, CNGRC fusion protein, human 3cediranib 3Photochemotherapy 3Neoadjuvant Therapy 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Mesothelioma, Malignant × defactinib × Thoracic × Clear all
NCT02004028 2024-02-20

Window of Opportunity Study of VS-6063 (Defactinib) in Surgical Resectable Malignant Pleural Mesothelioma Participants

Verastem, Inc.

Phase 2 Terminated
35 enrolled 15 charts
Other solid neoplasmThoracic

Mesothelioma, Malignant, Adenoma, Mesothelioma, Neoplasms, Mesothelial

NCT04201145 2020-11-17

Pembrolizumab + Defactinib In Pleural Mesothelioma

Dana-Farber Cancer Institute

Phase 1 Withdrawn
Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT01870609 2017-01-30

COMMAND

Verastem, Inc.

Phase 2 Terminated
344 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT02372227 2017-01-30

A Phase 1 Dose Escalation Study of VS-5584 Administered in Combination With VS-6063, in Subjects With Relapsed Malignant Mesothelioma

Verastem, Inc.

Phase 1 Terminated
21 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant

Data powered by HemOnc (CC BY 4.0) Colophon âš¡