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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 8Thoracic 1Lymphoid 1Gynecologic 1Genitourinary 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Carcinoma, Non-Small-Cell Lung 164Lung Neoplasms 61Small Cell Lung Carcinoma 24Neoplasms 10NSCLC 9Mesothelioma, Malignant 9Breast Neoplasms 8Pancreatic Neoplasms 7Ovarian Neoplasms 7Melanoma 6Head and Neck Neoplasms 6Colorectal Neoplasms 6Esophageal Neoplasms 5Stomach Neoplasms 4Neoplasm Metastasis 4Mesothelioma 4Kidney Neoplasms 4Brain Neoplasms 4Sarcoma 3Pleural Effusion, Malignant 3Liver Neoplasms 3Fallopian Tube Neoplasms 3Cholangiocarcinoma 3Carcinoma 3Adenocarcinoma of Lung 3Uterine Cervical Neoplasms 2Thymus Neoplasms 2Thymoma 2Small Cell Lung Cancer Limited Stage 2Skin Neoplasms 2

Interventions

pembrolizumab 5Taxes 2Polymerase Chain Reaction 2Nicotine 2Immunohistochemistry 2Gene Expression Profiling 2Fluorodeoxyglucose F18 2Counseling 2Bupropion 2motexafin gadolinium 1fluoromisonidazole 1Zinc Oxide 1Vorinostat 1Varenicline 1Tobacco Use Cessation Devices 1Rubidium-82 1Ritonavir 1Referral and Consultation 1Radiotherapy 1Psychiatric Rehabilitation 1Pemetrexed 1Paclitaxel 1Nivolumab 1Nicotine Replacement Therapy 1Mental Status and Dementia Tests 1Magnetic Resonance Spectroscopy 1Indinavir 1FPP(RGD)2 1Endoscopic Mucosal Resection 1Early Intervention, Educational 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Oropharyngeal Neoplasms × Drug Therapy × Thoracic × Clear all
NCT03329950 2024-03-28

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Celldex Therapeutics

Phase 1 Completed
132 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mouth Neoplasms, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Cholangiocarcinoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Hyper-IgM Immunodeficiency Syndrome

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