Announcements Trials
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Phase

Phase EARLY_PHASE1 1Phase 1 1

Status

Terminated 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Gynecologic 51Sarcoma 8Gastrointestinal 5Breast 5Genitourinary 3Thoracic 2Endocrine 2Other solid neoplasm 1Dermatologic 1CNS 1

Conditions

Lung Neoplasms 10Small Cell Lung Carcinoma 9Mesothelioma, Malignant 7Carcinoma, Non-Small-Cell Lung 5Neoplasm Metastasis 4Sarcoma 3Thymoma 2Ovarian Neoplasms 2Neoplasms 2Mesothelioma 2Lymphoma, Non-Hodgkin 2Head and Neck Neoplasms 2Glioma 2Fallopian Tube Neoplasms 2Colorectal Neoplasms 2Colonic Neoplasms 2Breast Neoplasms 2Waldenstrom Macroglobulinemia 1Triple Negative Breast Neoplasms 1Thyroid Neoplasms 1Thyroid Carcinoma, Anaplastic 1Thyroid Cancer, Papillary 1Thymic epithelial tumor 1Stomach Neoplasms 1Sezary Syndrome 1Rhabdomyosarcoma 1Rectal Neoplasms 1Pseudomyxoma Peritonei 1Prostatic Neoplasms 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1

Interventions

pembrolizumab 41Carboplatin 24Cyclophosphamide 20Paclitaxel 19Nivolumab 17Cisplatin 15fludarabine 14Gemcitabine 12aldesleukin 10Docetaxel 10Bevacizumab 9Magnetic Resonance Spectroscopy 8Trastuzumab 7Specimen Handling 7Drug Therapy 7Pemetrexed 6Oxaliplatin 6Ipilimumab 6Interleukin-2 6Fluorouracil 6Cetuximab 6Blood Specimen Collection 6sargramostim 5pegfilgrastim 5avelumab 5Topotecan 5Taxes 5Irinotecan 5palbociclib 4durvalumab 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Ovarian Neoplasms × Doxorubicin × Thoracic × Clear all
NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

M.D. Anderson Cancer Center

Phase 1 Terminated
221 enrolled
BreastDermatologicGenitourinaryGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT04213794 2025-02-20

TOASTIT

Mayo Clinic

Phase EARLY_PHASE1 Terminated
2 enrolled
GastrointestinalGynecologicOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Colonic Neoplasms, Fallopian Tube Neoplasms, Liposarcoma, Ovarian Neoplasms, Pelvic Neoplasms, Rectal Neoplasms, Rhabdomyosarcoma, Sarcoma, Stomach Neoplasms, Desmoplastic Small Round Cell Tumor

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