Announcements Trials
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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Gastrointestinal 1Breast 1

Conditions

Carcinoma, Non-Small-Cell Lung 545Lung Neoplasms 240Small Cell Lung Carcinoma 106Mesothelioma, Malignant 57Adenocarcinoma of Lung 41Mesothelioma 35Neoplasms 27Neoplasm Metastasis 25Colorectal Neoplasms 22Carcinoma 17Squamous Cell Carcinoma of Head and Neck 15Ovarian Neoplasms 15Adenocarcinoma, Bronchiolo-Alveolar 14Parkinson Disease 4, Autosomal Dominant Lewy Body 13Stomach Neoplasms 12Pancreatic Neoplasms 12Non-Squamous Non-Small Cell Lung Cancer 12Head and Neck Neoplasms 12Pleural Effusion, Malignant 8Melanoma 8Breast Neoplasms 8Sarcoma 7Extensive Stage Small Cell Lung Cancer 7Triple Negative Breast Neoplasms 6Thymoma 6Solitary Fibrous Tumor, Pleural 6NSCLC 6Endometrial Neoplasms 6Drug-Related Side Effects and Adverse Reactions 6Colonic Neoplasms 6

Interventions

Pemetrexed 2Carboplatin 2durvalumab 1Tretinoin 1Surgical Procedures, Operative 1Paclitaxel 1Observation 1Gemcitabine 1Cisplatin 1Bortezomib 1Azacitidine 1130-nm albumin-bound paclitaxel 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Pathologic Complete Response × Cisplatin × Thoracic × Clear all
NCT06694454 2026-06-04

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
60 enrolled
Thoracic

Pathologic Complete Response, Carcinoma, Non-Small-Cell Lung

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