Clinical Trials Browser

Interventional × Pleural Effusion × Thoracic × Clear all

NCT00761618 2026-04-16

Intrapleural Catheter Daily Versus Three Times a Week Drainage

Phase 2 Active not recruiting

Pleural Effusion, Pleural Effusion, Malignant

NCT01580618 2026-04-14

Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy

Phase 2/3 Terminated

20 enrolled 11 charts

Neoplasms, Pleural Effusion

NCT06892691 2026-02-04

PERFECT-MPE

Phase NA Recruiting

Neoplasms, Pleural Effusion

NCT04127149 2025-12-19

EPEMedG

Phase NA Completed

Abortion, Spontaneous, Cholecystitis, Cysts, Phlebitis, Pleural Effusion, Pneumonia, Pregnancy, Ectopic, Renal Colic

NCT06538376 2025-10-29

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

Phase NA Recruiting

Other solid neoplasmThoracic

Airway Obstruction, Pulmonary Atelectasis, Hemothorax, Mesothelioma, Pleural Effusion, Pneumonia, Pneumothorax, Pulmonary Edema, Pulmonary Embolism, Respiratory Paralysis, Rib Fractures

NCT06210685 2025-08-11

The ACES Study for Aseptic Pleural Effusion

Phase NA Active not recruiting

Pleural Effusion, Pleural Effusion, Malignant

NCT06959719 2025-05-07

ARMSTRONG

Phase NA Recruiting

MyeloidThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Pleural Effusion, Pleural Effusion, Malignant

NCT06946498 2025-04-27

FLAT

Phase NA Recruiting

Other solid neoplasmThoracic

Mesothelioma, Malignant, Lung Neoplasms, Mesothelioma, Pleural Effusion, Pleural Effusion, Malignant

NCT03167281 2025-02-21

ELEVATE

Phase 4 Withdrawn

Lung Neoplasms, Pleural Diseases, Pleural Effusion, Pneumothorax, Pulmonary Embolism

NCT01766739 2024-10-26

Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma

Phase 1 Completed

Lung Neoplasms, Pleural Effusion

NCT06421610 2024-05-20

OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.

Phase 1 Recruiting

Pleural Effusion, Pleural Neoplasms, Pleural Effusion, Malignant

NCT03449602 2023-03-29

MICRO

Phase NA Unknown

Lung Neoplasms, Neoplasm Metastasis, Pleural Effusion, Tuberculosis, Pleural Effusion, Malignant

NCT00858364 2022-11-30

Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy

Phase 3 Terminated

2,549 enrolled 19 charts

Classical hematologyThoracic

Anemia, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms, Pleural Effusion, Pleural Effusion, Malignant

NCT05539183 2022-09-14

Collection of Pleural Effusion Fluid

Phase NA Unknown

Neoplasm Metastasis, Pleural Effusion

NCT05121233 2021-11-16

Local Anesthesia Versus Combined Local Anesthesia With Single Dose Analgesia on Pain Control During Thoracic Ultrasound Guided Procedures

Phase 4 Unknown

Lung Neoplasms, Pleural Effusion, Pleural Neoplasms, Pneumothorax, Empyema, Pleural, Respiratory Aspiration

NCT01999985 2020-11-27

Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC)

Phase 1 Completed

25 enrolled 10 charts

Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Pleural Diseases, Pleural Effusion, Pleural Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Pleural Effusion, Malignant

NCT04233359 2020-09-28

A Randomised Study Evaluating Diagnostics of Pleural Effusion Among Patients Suspect of Cancer.

Phase NA Terminated

Pleural Effusion, Pleural Effusion, Malignant

NCT03543462 2020-05-22

DRAGON

Phase 4 Completed

GynecologicThoracic

Ovarian Neoplasms, Pleural Effusion

NCT00299962 2020-03-18

Gene Therapy for Pleural Malignancies

Phase 1 Completed

Other solid neoplasmThoracic

Mesothelioma, Malignant, Pleural Effusion

NCT03678090 2020-03-05

The Safety and Efficacy of Fibrinolysis in Patients With an Indwelling Pleural Catheter for Multi-loculated Malignant Pleural Effusion.

Phase 2 Withdrawn

Lung Neoplasms, Pleural Effusion

NCT04254445 2020-02-18

Use of Guidance Videos to Increase Engagement and Decrease Anxiety in Patients Undergoing Pleural Tap

Phase NA Unknown

Pleural Effusion, Pleural Effusion, Malignant

NCT01722149 2019-08-07

Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma

Phase EARLY_PHASE1 Completed

Other solid neoplasmThoracic

Mesothelioma, Malignant, Pleural Effusion

NCT03973957 2019-06-04

TOPIC

Phase NA Unknown

Pleural Diseases, Pleural Effusion, Pleural Effusion, Malignant

NCT02975921 2019-01-11

Betadine Pleurodesis Via Tunneled Pleural Catheters

Phase 4 Withdrawn

Bronchiolitis Obliterans Syndrome, Pleural Effusion, Pleural Effusion, Malignant

NCT02500277 2018-08-31

COFFEE

Phase NA Completed

Neoplasms, Pleural Effusion, Pleurisy, Tuberculosis

NCT01612975 2018-02-15

The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection

Phase 2 Terminated

Lung Neoplasms, Pleural Effusion, Pleural Effusion, Malignant

NCT01952327 2017-06-14

ADEPT

Phase NA Terminated

Pleural Effusion

NCT00942825 2017-05-24

CBP08-02

Phase 2 Completed

195 enrolled 8 charts

Lung Neoplasms, Neoplasm Metastasis, Pleural Effusion

NCT00753714 2016-10-17

ZELIG

Phase 2 Completed

124 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion

NCT00402896 2016-03-09

Malignant Pleural Effusion With ZD6474

Phase 2 Terminated

28 enrolled 5 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion

NCT00896285 2015-07-20

TIME-1

Phase NA Completed

Neoplasms, Pleural Effusion, Pleural Effusion, Malignant

NCT00799240 2014-11-07

IMPACT

Phase 2 Completed

Insulin-Like Growth Factor I, Resistance To, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion

NCT01776372 2014-05-13

Comparison of Pleural Drainage Systems on Reducing Pleural Effusion Formation Following Lung Resection

Phase NA Completed

Lung Neoplasms, Pleural Effusion

NCT01854866 2013-10-01

Safety and Effectiveness Study of Tumor Cell-derived Microparticles to Treat Malignant Ascites and Pleural Effusion

Phase 2 Unknown

Ascites, Pleural Effusion, Pleural Effusion, Malignant

NCT00005906 2010-04-30

Treatment With Octreotide in Patients With Lymphangioleiomyomatosis

Phase 2 Completed

4 enrolled 8 charts

Ascites, Chylous Ascites, Chylothorax, Lymphangiomyoma, Pleural Effusion, Lymphangioleiomyomatosis

NCT00789087 2008-11-11

Talc Pleurodesis in Patients With Recurrent Malignant Pleural Effusion

Phase 4 Completed

Pleural Effusion, Pleural Effusion, Malignant

NCT00720954 2008-07-23

Rigid Thoracoscopy Versus CT-Guided Pleural Needle Biopsy

Phase NA Completed

Other solid neoplasmThoracic

Disease, Mesothelioma, Pleural Diseases, Pleural Effusion

NCT00430664 2007-02-02

A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis

Phase NA Unknown

Pleural Effusion, Pneumothorax, Pleural Effusion, Malignant