Announcements Trials
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Phase

Phase 1 3

Status

Terminated 1Recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Head & Neck 7Thoracic 3Gastrointestinal 2Breast 2Genitourinary 1Dermatologic 1

Conditions

Carcinoma, Non-Small-Cell Lung 9Neoplasms 7Triple Negative Breast Neoplasms 4Small Cell Lung Carcinoma 4Stomach Neoplasms 3Squamous Cell Carcinoma of Head and Neck 3Pancreatic Neoplasms 2Ovarian Neoplasms 2Mesothelioma 2Melanoma 2Cholangiocarcinoma 2Carcinoma, Merkel Cell 2Carcinoma, Hepatocellular 2Urinary Bladder Neoplasms 1Neoplasm Metastasis 1Head and Neck Neoplasms 1Esophageal Neoplasms 1Colorectal Neoplasms 1Central Nervous System Neoplasms 1Carcinoma, Renal Cell 1Carcinoma, Neuroendocrine 1Anophthalmia with pulmonary hypoplasia 1

Interventions

pembrolizumab 70Nivolumab 24Docetaxel 17Cisplatin 15Paclitaxel 13Carboplatin 12Gemcitabine 8Cetuximab 8Ipilimumab 7durvalumab 6avelumab 6atezolizumab 6Radiotherapy 6Cyclophosphamide 6spartalizumab 5Trastuzumab 5Taxes 5Pemetrexed 5Erlotinib Hydrochloride 5tremelimumab 4cemiplimab 4Specimen Handling 4Leucovorin 4Interleukin-2 4Fluorouracil 4Capecitabine 4Biopsy 4Albumin-Bound Paclitaxel 4130-nm albumin-bound paclitaxel 4utomilumab 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Squamous Cell Carcinoma of Head and Neck × budigalimab × Thoracic × Clear all
NCT05005403 2026-05-13

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

AbbVie

Phase 1 Recruiting
694 enrolled
BreastGastrointestinalHead & NeckThoracic

Anophthalmia with pulmonary hypoplasia, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Triple Negative Breast Neoplasms

NCT02988960 2026-01-09

A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors

AbbVie

Phase 1 Active not recruiting
163 enrolled
DermatologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms

NCT06158958 2025-10-27

A Study to Assess the Safety, Pharmacokinetics, and Efficacy of Intravenous (IV) ABBV-303, as Monotherapy and in Combination With IV Infused Budigalimab (ABBV-181), in Adults With Advanced Solid Tumors

AbbVie

Phase 1 Terminated
27 enrolled
GenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell

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