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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1Gynecologic 1Gastrointestinal 1

Conditions

Carcinoma, Non-Small-Cell Lung 27Ovarian Neoplasms 14Lung Neoplasms 12Melanoma 11Colorectal Neoplasms 9Breast Neoplasms 9Stomach Neoplasms 7Pancreatic Neoplasms 7Triple Negative Breast Neoplasms 6Neoplasms 6Neoplasm Metastasis 6Mesothelioma 6Carcinoma, Merkel Cell 5Small Cell Lung Carcinoma 4Multiple Myeloma 4Mesothelioma, Malignant 4Head and Neck Neoplasms 4Esophageal Neoplasms 4Carcinoma, Transitional Cell 4Carcinoma, Renal Cell 4Carcinoma, Hepatocellular 4Uterine Cervical Neoplasms 3Urogenital Neoplasms 3Urinary Bladder Neoplasms 3Squamous Cell Carcinoma of Head and Neck 3Recurrence 3Liver Neoplasms 3Cholangiocarcinoma 3Carcinoma, Squamous Cell 3Thymoma 2

Interventions

pembrolizumab 3Quality of Life 2Proton Therapy 2Immunotherapy 2Drug Therapy 2fludarabine 1epacadostat 1bosutinib 1amrubicin 1alovudine 1Tumor Burden 1Sunitinib 1Radiotherapy 1Radiosurgery 1Radiation 1Plicamycin 1Pemetrexed 1Patient Reported Outcome Measures 1Molecular Diagnostic Techniques 1Histocompatibility Testing 1Erlotinib Hydrochloride 1Cyclophosphamide 1Blood Specimen Collection 1Biological Therapy 1Bevacizumab 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Thymus Neoplasms × fludarabine × Thoracic × Clear all
NCT06885697 2026-06-05

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
100 enrolled
GastrointestinalGynecologicOther solid neoplasmThoracic

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

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