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Phase

Phase 2/3 1

Status

Completed 9Terminated 3Active not recruiting 3Withdrawn 1Unknown 1Recruiting 1Not yet recruiting 1Approved for marketing 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 15Endocrine 15Thoracic 1Plasma cell 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Gynecologic 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Carcinoma, Non-Small-Cell Lung 325Lung Neoplasms 237Small Cell Lung Carcinoma 79Colorectal Neoplasms 30NSCLC 25Breast Neoplasms 22Neoplasms 16Adenocarcinoma of Lung 16Disease 15Neoplasm Metastasis 12Stomach Neoplasms 10Melanoma 10Ovarian Neoplasms 9Brain Neoplasms 9Uterine Cervical Neoplasms 8Triple Negative Breast Neoplasms 8Squamous Cell Carcinoma of Head and Neck 8Pleural Effusion, Malignant 8Motor Activity 8Mesothelioma, Malignant 8Head and Neck Neoplasms 8Esophageal Neoplasms 7Endometrial Neoplasms 7Multiple Pulmonary Nodules 6Mesothelioma 6Carcinoma, Hepatocellular 6Thymoma 5Small Cell Lung Cancer Extensive Stage 5SCLC, Extensive Stage 5Recurrence 5

Interventions

trametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Not yet recruiting × Thyroid Cancer, Papillary × Thoracic × Clear all
NCT07440290 2026-02-27

DETERMINE

Cancer Research UK

Phase 2/3 Not yet recruiting
30 enrolled
CNSEndocrineGastrointestinalGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

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