Announcements Trials
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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Breast 50Gynecologic 3Thoracic 1Sarcoma 1Plasma cell 1Genitourinary 1Dermatologic 1

Conditions

Lung Neoplasms 10Small Cell Lung Carcinoma 9Mesothelioma, Malignant 7Carcinoma, Non-Small-Cell Lung 5Neoplasm Metastasis 4Sarcoma 3Thymoma 2Ovarian Neoplasms 2Neoplasms 2Mesothelioma 2Lymphoma, Non-Hodgkin 2Head and Neck Neoplasms 2Glioma 2Fallopian Tube Neoplasms 2Colorectal Neoplasms 2Colonic Neoplasms 2Breast Neoplasms 2Waldenstrom Macroglobulinemia 1Triple Negative Breast Neoplasms 1Thyroid Neoplasms 1Thyroid Carcinoma, Anaplastic 1Thyroid Cancer, Papillary 1Thymic epithelial tumor 1Stomach Neoplasms 1Sezary Syndrome 1Rhabdomyosarcoma 1Rectal Neoplasms 1Pseudomyxoma Peritonei 1Prostatic Neoplasms 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1

Interventions

pembrolizumab 47Nivolumab 22Cyclophosphamide 10Carboplatin 9spartalizumab 8atezolizumab 7Gemcitabine 7130-nm albumin-bound paclitaxel 7fludarabine 6Ipilimumab 5Cisplatin 5durvalumab 4budigalimab 4avelumab 4Pemetrexed 4Paclitaxel 4Magnetic Resonance Spectroscopy 4Leucovorin 4Irinotecan 4Interleukin-2 4Immune Checkpoint Inhibitors 4Docetaxel 4Bevacizumab 4cemiplimab 3cabozantinib 3aldesleukin 3Standard of Care 3Specimen Handling 3Oxaliplatin 3Fluorouracil 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Triple Negative Breast Neoplasms × Doxorubicin × Thoracic × Clear all
NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

M.D. Anderson Cancer Center

Phase 1 Terminated
221 enrolled
BreastDermatologicGenitourinaryGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

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