Announcements Trials
Browse Landscape

Phase

Phase 1/2 3Phase 1 3Phase 2 1

Status

Completed 3

Sponsor Class

NIH 3

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 74Myeloid 32Lymphoid 11Head & Neck 5Other solid neoplasm 4Dermatologic 4Thoracic 3Sarcoma 3Gynecologic 2Gastrointestinal 2CNS 2Breast 2Tumor-Agnostic 1Plasma cell 1Other neoplasm 1Genitourinary 1Classical hematology 1

Conditions

Carcinoma, Non-Small-Cell Lung 3Small Cell Lung Carcinoma 2Mesothelioma, Malignant 2Lung Neoplasms 2Pleural Effusion, Malignant 1Neoplasm Metastasis 1Esophageal Neoplasms 1

Interventions

pembrolizumab 159Carboplatin 147Cisplatin 130Pemetrexed 103Paclitaxel 89Nivolumab 71Radiotherapy 69Docetaxel 62Erlotinib Hydrochloride 58Gemcitabine 57Etoposide 44osimertinib 43Bevacizumab 43Cyclophosphamide 42durvalumab 41atezolizumab 35Cetuximab 33Radiosurgery 26130-nm albumin-bound paclitaxel 26fludarabine 23Ipilimumab 23Radiation 21Magnetic Resonance Spectroscopy 21Irinotecan 21Taxes 20Oxaliplatin 20Fluorouracil 20Gefitinib 19Everolimus 19Topotecan 18

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Decitabine × Thoracic × Clear all
NCT00037817 2019-09-30

Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
34 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT00019825 2015-04-29

Decitabine in Treating Patients With Unresectable Lung or Esophageal Cancer or Malignant Mesothelioma of the Pleura

National Cancer Institute (NCI)

Phase 1 Completed
GastrointestinalOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pleural Effusion, Malignant, Small Cell Lung Carcinoma

NCT00084981 2013-09-30

Decitabine and Valproic Acid in Treating Patients With Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

Phase 1 Completed
25 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

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