Clinical Trials

Phase 2 Active not recruiting

Thymic epithelial tumor, Mediastinal Neoplasms, Thymoma

NCT01025089 2026-01-07

Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic Carcinoma

18 enrolled

Thymoma

NCT04224337 2025-12-31

Phase II Study of Durvalumab ,Doxorubicin, and Ifosfamide in Pulmonary Sarcomatoid Carcinoma

16 enrolled

BreastDermatologicGenitourinaryGynecologicThoracic

Carcinoma, Non-Small-Cell Lung

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT04213794 2025-02-20

TOASTIT

Phase EARLY_PHASE1 Terminated

2 enrolled

GastrointestinalGynecologicOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Colonic Neoplasms, Fallopian Tube Neoplasms, Liposarcoma, Ovarian Neoplasms, Pelvic Neoplasms, Rectal Neoplasms, Rhabdomyosarcoma, Sarcoma, Stomach Neoplasms, Desmoplastic Small Round Cell Tumor

NCT00856037 2023-09-26

Topotecan Hydrochloride and Doxorubicin Hydrochloride in Treating Relapsed or Refractory Small Cell Lung Cancer

22 enrolled

Small Cell Lung Carcinoma

NCT02566993 2021-10-28

ATLANTIS

Phase 3 Completed

613 enrolled 46 charts

Small Cell Lung Carcinoma

NCT00859495 2020-08-25

Trimodal Lung-Sparing Treatment of Pleural Mesothelioma

Phase 2 Terminated

9 enrolled 4 charts

Mesothelioma, Malignant

NCT00036790 2019-12-17

Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced Cancer

BreastDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Hypopharyngeal Neoplasms, Immunoblastic Lymphadenopathy, Laryngeal Neoplasms, Leukemia, Leukemia, Hairy Cell, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mouth Neoplasms, Multiple Myeloma, Mycosis Fungoides, Myeloproliferative Disorders, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Prostatic Neoplasms, Sezary Syndrome, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Small Cell Lung Carcinoma

NCT00483509 2019-10-04

NGR007

28 enrolled 10 charts

Small Cell Lung Carcinoma

NCT02261805 2018-04-23

A Phase I/II Study of Ganetespib in Combination With Doxorubicin

Phase 1/2 Terminated

11 enrolled 7 charts

GynecologicOther solid neoplasmThoracic

Neoplasms, Small Cell Lung Carcinoma

NCT03034850 2017-01-27

Thrombin Generation and Platelet Activation in CRS/HIPEC

Completed

27 enrolled

Mesothelioma, Peritoneal Neoplasms, Pseudomyxoma Peritonei

NCT00634205 2015-02-12

Phase II Study of Valproate and Doxorubicin in Malignant Mesothelioma

45 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT00759824 2015-02-12

A Phase II Study of Doxorubicin, Cyclophosphamide and Vindesine With Valproic Acid in Patients With Refractory or Relapsing Small Cell Lung Cancer After Platinum Derivatives and Etoposide

64 enrolled

Small Cell Lung Carcinoma

NCT00024271 2014-01-06

Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Peritoneal Cancer

Phase 2 Unknown

Mesothelioma, Malignant

NCT00002822 2013-12-19

Combination Chemotherapy Followed by Radiation Therapy in Patients With Small Cell Lung Cancer

Phase 3 Completed

400 enrolled

Lung Neoplasms

NCT00003364 2013-12-19

Radiation Therapy Plus Combination Chemotherapy In Treating Patients With Limited Stage Small Cell Lung Cancer

Phase 3 Completed

398 enrolled

Lung Neoplasms

NCT00003034 2013-11-06

ONCONASE Plus Doxorubicin Versus Doxorubicin Alone For Patients With Malignant Pleural or Peritoneal Mesothelioma Who Have Had No More Than One Prior Chemotherapy Regimen

Phase 3 Unknown

300 enrolled

Mesothelioma, Malignant

NCT00003696 2013-09-17

Combination Chemotherapy in Treating Patients Who Have Extensive-Stage Small Cell Lung Cancer

Phase 3 Unknown

250 enrolled

Lung Neoplasms

NCT00003847 2013-09-05

VX-710, Doxorubicin, and Vincristine for the Treatment of Patients With Recurrent Small Cell Lung Cancer

Phase 2 Terminated

36 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00002608 2013-07-10

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

CNSEndocrineGastrointestinalHead & NeckOther solid neoplasmSarcomaThoracic

30 enrolled

Familial ependymoma, Thyroid Cancer, Papillary, Mesothelioma, Malignant, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Medulloblastoma, Oligodendroglioma, Pheochromocytoma, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Adenocarcinoma, Follicular, Adrenocortical Carcinoma, Carcinoma, Medullary, Glioma, Subependymal, Gliosarcoma, Optic Nerve Glioma, Thyroid Carcinoma, Anaplastic

NCT00004930 2013-06-19

Inhaled Doxorubicin in Treating Patients With Primary Lung Cancer or Lung Metastases

Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT00020124 2012-03-15

Inhaled Doxorubicin in Treating Patients With Advanced Solid Tumors Affecting the Lungs

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT00002858 2009-02-09

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Small Cell Lung Cancer

Phase 3 Unknown

280 enrolled