Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase NA 2Phase 4 1Phase 3 1

Status

Completed 3Withdrawn 1Unknown 1Terminated 1Active not recruiting 1

Sponsor Class

OTHER 4INDUSTRY 2NETWORK 1

Study Type

Interventional 7Observational 1

Sponsor

Cancer Type

Thoracic 7Gastrointestinal 6Lymphoid 5Breast 4Plasma cell 3Dermatologic 3CNS 2Other neoplasm 1Other hematologic neoplasm 1Head & Neck 1Gynecologic 1Genitourinary 1

Conditions

Pleural Effusion, Malignant 4Carcinoma, Non-Small-Cell Lung 3Neoplasm Metastasis 1Exanthema 1

Interventions

Carboplatin 1152Cisplatin 876Pemetrexed 834pembrolizumab 608Paclitaxel 598Docetaxel 535Gemcitabine 424Radiotherapy 377Erlotinib Hydrochloride 367Nivolumab 322Bevacizumab 322Etoposide 295durvalumab 254Drug Therapy 233osimertinib 218atezolizumab 208Radiosurgery 190Gefitinib 177Vinorelbine 145130-nm albumin-bound paclitaxel 124Magnetic Resonance Spectroscopy 121Ipilimumab 118Cetuximab 113anlotinib 104tislelizumab 103Topotecan 101Cyclophosphamide 101Taxes 99Irinotecan 95Albumin-Bound Paclitaxel 92

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Interventional × Doxycycline × Thoracic × Clear all
NCT06120140 2026-06-05

COCOON

Janssen Research & Development, LLC

Phase 2 Active not recruiting
305 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00002872 2023-06-22

Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions

Eastern Cooperative Oncology Group

Phase 3 Completed
480 enrolled
Thoracic

Neoplasm Metastasis, Pleural Effusion, Malignant

NCT02583282 2022-10-06

A Study to Compare the Efficacy and Safety of Intrapleural Doxycycline Versus Iodopovidone for Performing Pleurodesis in Malignant Pleural Effusion

Post Graduate Institute of Medical Education and Research, Chandigarh

Phase NA Completed
100 enrolled
Thoracic

Pleural Effusion, Malignant

NCT01411202 2020-09-25

OPUS

Ottawa Hospital Research Institute

Phase 2 Unknown
40 enrolled
Thoracic

Pleural Effusion, Malignant

NCT02623959 2019-08-07

Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis

M.D. Anderson Cancer Center

Phase 4 Terminated
3 enrolled 4 charts
Thoracic

Pleural Effusion, Malignant

NCT01465802 2019-01-09

ARCHER 1042

Pfizer

Phase 2 Completed
236 enrolled 24 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00803842 2015-02-26

Erlotinib Pharmacokinetics During Doxycycline Treatment for Erlotinib-induced Rash

Northwestern University

Phase NA Withdrawn
Thoracic

Carcinoma, Non-Small-Cell Lung, Exanthema

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