Clinical Trials

BreastDermatologicGenitourinaryGynecologicThoracic

Lung Neoplasms

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT05800587 2025-04-04

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

Phase 2 Recruiting

280 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT05049863 2024-12-05

Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)

Phase 1 Terminated

17 enrolled

Small Cell Lung Carcinoma

NCT03879798 2024-10-10

DS-3201b and Irinotecan for Patients With Recurrent Small Cell Lung Cancer

22 enrolled 9 charts

Small Cell Lung Carcinoma

NCT04173325 2022-06-14

Feasibility and Safety Study of Nivolumab With Irinotecan for Small Cell Lung Cancer

Phase 1 Terminated

10 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00695292 2021-11-22

Irinotecan, Carboplatin, and Sunitinib in First Line Extensive-Stage Small Cell Lung Cancer

37 enrolled 10 charts

Small Cell Lung Carcinoma

NCT00025285 2021-09-09

Combination Chemotherapy Plus Thalidomide in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

46 enrolled

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04985201 2021-08-09

Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy

40 enrolled

Small Cell Lung Carcinoma

NCT04543916 2021-03-03

Venetoclax and Irinotecan in Relapsed/Refractory SCLC

Phase 1/2 Withdrawn

Small Cell Lung Carcinoma

NCT04757779 2021-02-17

A Single-arm, Phase Ⅱ Clinical Trial of Anlotinib Hydrochloride Combined With Irinotecan or Docetaxel for Second Line Treatment of Nonsensitive Relapsed Small-cell Lung Cancer

40 enrolled

Small Cell Lung Carcinoma

NCT02171325 2021-02-03

Study of Different Doses of Irinotecan and Cisplatin for First-line Extensive-stage Small-cell Lung Cancer Treatment

54 enrolled

Small Cell Lung Carcinoma

NCT04453930 2020-07-01

A Study of Sequential Therapy of Camrelizumab Combined With Chemotherapy（Irinotecan Plus Platinum）and With Apatinib in Participants With Untreated Advanced Small Cell Lung Cancer（SCLC）

60 enrolled

Small Cell Lung Carcinoma

NCT03613753 2020-02-05

Irinotecan Plus Lobaplatin Versus Irinotecan in the Second-line Treatment of Small Cell Lung Cancer

72 enrolled

Recurrence, Small Cell Lung Carcinoma

NCT02275806 2019-08-21

Cisplatin/Irinotecan With Concurrent Radiation for Inoperable NSCLC

Phase 2 Terminated

4 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00465907 2019-02-11

Study of Weekly Paclitaxel, Carboplatin and Irinotecan to Treat Lung Cancer

Phase 2 Terminated

7 enrolled

Lung Neoplasms

NCT03651219 2018-08-29

Mesylate Apatinib Combined With Irinotecan in Treatment of Recurrent Small Cell Lung Cancer

Phase 3 Unknown

90 enrolled

Small Cell Lung Carcinoma

NCT02331251 2018-07-02

Study of Pembrolizumab Plus Chemotherapy in Patients With Advanced Cancer (PembroPlus)

BreastGastrointestinalSarcomaThoracic

81 enrolled

Breast Neoplasms, Pancreatic Neoplasms, Sarcoma, Small Cell Lung Carcinoma

NCT02423954 2018-07-02

NivoPlus

GastrointestinalGenitourinaryThoracic

33 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Pancreatic Neoplasms, Colorectal Neoplasms

NCT01607554 2018-05-22

Irinotecan for Previously Treated, Advanced, Non-Small Cell Lung Cancer

2 enrolled 6 charts

Carcinoma, Non-Small-Cell Lung

NCT00387660 2018-01-10

Irinotecan and Carboplatin in Treating Patients With Metastatic or Recurrent Small Cell Lung Cancer

80 enrolled 8 charts

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00856830 2017-07-17

Bendamustine With Irinotecan Followed by Etoposide/Carboplatin for Patients With Extensive Stage Small Cell Lung Cancer

Phase 1/2 Completed

30 enrolled 12 charts

Small Cell Lung Carcinoma

NCT00004095 2017-04-18

Irinotecan Plus Gemcitabine in Treating Patients With Unresectable or Metastatic Solid Tumors

BreastGastrointestinalGenitourinaryThoracic

38 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Kidney Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Small Cell Lung Carcinoma

NCT00449020 2016-12-15

Carboplatin, Irinotecan, and Radiation Therapy Followed By Docetaxel in Treating Patients With Newly Diagnosed Stage III Non-Small Cell Lung Cancer

32 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02348450 2016-12-05

Irinotecan Plus Cisplatin Compared With Etoposide Plus Cisplatin for Extensive Stage Small-cell Lung Cancer

Phase 4 Unknown

308 enrolled

Small Cell Lung Carcinoma

NCT00144989 2016-09-22

A Study Comparing Irinotecan and Cisplatin (IP) With Etoposide and Cisplatin (EP) Following EP/TRT for LD-SCLC

Phase 3 Completed

281 enrolled

Small Cell Lung Carcinoma

NCT00193375 2016-08-10

Irinotecan, Carboplatin and Radiation Therapy Followed by Bevacizumab in Limited Stage Small Cell Lung Cancer

60 enrolled 7 charts

Lung Neoplasms

NCT00004139 2016-07-20

Gemcitabine Plus Docetaxel or Irinotecan in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

80 enrolled

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00005972 2016-07-14

Combination Chemotherapy in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer

73 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00003900 2016-07-06

Irinotecan With Docetaxel in Treating Patients With Recurrent or Metastatic Non-small Cell Lung Cancer

48 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00072527 2016-07-06

Cisplatin and Irinotecan Followed by Carboplatin, Etoposide, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

78 enrolled

Lung Neoplasms

NCT01977235 2016-04-01

TDICC

110 enrolled

Small Cell Lung Carcinoma

NCT00391586 2015-08-17

Erlotinib and Standard Platinum-Based Chemotherapy for Newly Diagnosed, Advanced Non-Small Cell Carcinoma of the Lung

Phase 2 Terminated

45 enrolled 4 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00052494 2015-07-23

Combination Chemotherapy and Imatinib Mesylate in Treating Patients With Extensive-Stage Small Cell Lung Cancer

9 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00240097 2014-11-27

Study of Sequential Topoisomerase, Irinotecan/Oxaliplatin - Etoposide /Carboplatin in Extensive Small Cell Lung Cancer (SCLC)

30 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung

NCT01654081 2014-05-30

A Protocol of Irinotecan for Carcinoma of the Lung

Phase 2 Withdrawn

Lung Neoplasms

NCT00349492 2013-12-04

A Study Comparing Etoposide/Cisplatin With Irinotecan/Cisplatin to Treat Extensive Disease Small Lung Cancer

Phase 3 Completed

372 enrolled

Small Cell Lung Carcinoma

NCT00022308 2013-09-02

Chemotherapy and Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00003111 2013-07-25

Combination Chemotherapy Followed by Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer

10 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00248482 2013-04-29

Imatinib Mesylate After Irinotecan and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer

6 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00280787 2013-02-05

Induction Chemotherapy Using Paclitaxel, Carboplatin, CPT-11 With Pegfilgrastim

24 enrolled

Carcinoma, Non-Small-Cell Lung

NCT00346801 2012-10-22

CPT-11/Cisplatin and Celecoxib With Radiation Therapy for Patients With Unresectable Non-Small Cell Lung Cancer (NSCLC)

20 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00469898 2012-07-27

Irinotecan and Carboplatin as First-Line Therapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer

50 enrolled 11 charts

Lung Neoplasms

NCT00073866 2012-07-19

Combination Chemotherapy and Celecoxib in Treating Patients With Advanced Non-Small Cell Lung Cancer

Phase 1/2 Completed

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01635400 2012-07-09

Study of Relationship Between UGT1A1 Gene Polymorphism and Toxicity and Efficacy of Irinotecan in Small Cell Lung Cancer

50 enrolled

Small Cell Lung Carcinoma

NCT00182806 2012-03-06

Irinotecan and Gemcitabine in Treating Patients With Recurrent or Progressive Stage III or Stage IV Non-Small Cell Lung Cancer

38 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00614965 2011-05-23

Irinotecan Plus Cisplatin vs Pemetrexed Plus Cisplatin as 2nd Line in NSCLC Stage IIIB/IV

124 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT00193349 2010-06-28

Gleevec Combined With Camptosar Plus Paraplatin in Previously Untreated Extensive Stage Small Cell Lung Cancer

60 enrolled

Lung Neoplasms

NCT00294931 2010-06-28

Irinotecan, Carboplatin, Bevacizumab in the Treatment of Patients With Extensive Stage Small Cell Lung Cancer

50 enrolled