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Phase

Phase 1 3Phase EARLY_PHASE1 1

Status

Recruiting 5Completed 4Unknown 1Terminated 1

Sponsor Class

INDUSTRY 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Other solid neoplasm 10Other hematologic neoplasm 9Lymphoid 9Breast 8Tumor-Agnostic 7Genitourinary 6Dermatologic 6Thoracic 4CNS 4Sarcoma 3Plasma cell 3Myeloid 3Gynecologic 3Gastrointestinal 1Classical hematology 1

Conditions

Carcinoma, Non-Small-Cell Lung 3Sarcoma, Synovial 1Sarcoma 1Rhabdoid Tumor 1Neoplasms 1Mesothelioma 1Lymphoma, Non-Hodgkin 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Hematologic Neoplasms 1

Interventions

Carboplatin 463Cisplatin 379Paclitaxel 313Pemetrexed 300Docetaxel 242Erlotinib Hydrochloride 240Gemcitabine 232pembrolizumab 173Radiotherapy 172Bevacizumab 169Nivolumab 130Etoposide 106Gefitinib 95Vinorelbine 84durvalumab 71atezolizumab 68Cetuximab 65Topotecan 61Drug Therapy 57Ipilimumab 55Irinotecan 54osimertinib 53Radiosurgery 52Afatinib 51Surveys and Questionnaires 38130-nm albumin-bound paclitaxel 38Albumin-Bound Paclitaxel 37Taxes 35Cyclophosphamide 35Surgical Procedures, Operative 34

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × Itraconazole × Thoracic × Clear all
NCT02157883 2025-11-19

Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva)

AstraZeneca

Phase 1 Completed
39 enrolled 18 charts
Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT04537715 2025-02-19

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

Ipsen

Phase 1 Completed
42 enrolled 39 charts
LymphoidOther hematologic neoplasmOther solid neoplasmSarcomaThoracic

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mesothelioma, Sarcoma, Sarcoma, Synovial, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Hematologic Neoplasms

NCT06348888 2024-06-20

A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants

Bayer

Phase 1 Completed
30 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02357836 2021-05-03

Neoadjuvant Itraconazole in Non-small Cell Lung Cancer

University of Texas Southwestern Medical Center

Phase EARLY_PHASE1 Completed
13 enrolled 12 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

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