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Phase

Phase 2 23Phase 1/2 8Phase 1 5Phase 3 2Phase 2/3 2

Status

Completed 3Terminated 1Recruiting 1

Sponsor Class

OTHER 3INDUSTRY 2

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 147Sarcoma 62Other solid neoplasm 16Dermatologic 15Lymphoid 8Gastrointestinal 7Tumor-Agnostic 5Thoracic 5Other hematologic neoplasm 4Gynecologic 4Genitourinary 4Breast 4Endocrine 3NET 2Head & Neck 1

Conditions

Small Cell Lung Carcinoma 2Sarcoma 2Carcinoma, Non-Small-Cell Lung 2Triple Negative Breast Neoplasms 1Stomach Neoplasms 1Ovarian Neoplasms 1Neoplasms, Second Primary 1Neoplasm Metastasis 1Mesothelioma 1Melanoma 1Lung Neoplasms 1Head and Neck Neoplasms 1Esophageal Neoplasms 1Central Nervous System Neoplasms 1Breast Neoplasms 1

Interventions

pembrolizumab 159Carboplatin 147Cisplatin 130Pemetrexed 103Paclitaxel 89Nivolumab 71Radiotherapy 69Docetaxel 62Erlotinib Hydrochloride 58Gemcitabine 57Etoposide 44osimertinib 43Bevacizumab 43Cyclophosphamide 42durvalumab 41atezolizumab 35Cetuximab 33Radiosurgery 26130-nm albumin-bound paclitaxel 26fludarabine 23Ipilimumab 23Radiation 21Magnetic Resonance Spectroscopy 21Irinotecan 21Taxes 20Oxaliplatin 20Fluorouracil 20Gefitinib 19Everolimus 19Topotecan 18

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1 × Temozolomide × Thoracic × Clear all
NCT06931626 2025-11-12

Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer

Nerviano Medical Sciences

Phase 1 Recruiting
10 enrolled
Thoracic

Small Cell Lung Carcinoma

NCT00629343 2025-06-05

Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide

Columbia University

Phase 1 Completed
27 enrolled 7 charts
Other solid neoplasmSarcomaThoracic

Mesothelioma, Sarcoma

NCT03150810 2024-12-20

Study to Assess Safety, Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Participants With Locally Advanced or Metastatic Solid Tumors

BeiGene

Phase 1 Completed
139 enrolled 36 charts
BreastGastrointestinalGynecologicHead & NeckSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04541407 2023-05-16

Temodar Plus Tyrosine Kinase Inhibitors for Progressive CNS Disease

University of Colorado, Denver

Phase 1 Completed
1 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00629187 2012-04-27

CN-306

Tufts Medical Center

Phase 1 Terminated
2 enrolled
BreastCNSDermatologicThoracic

Breast Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Central Nervous System Neoplasms, Neoplasms, Second Primary

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