Announcements Trials
Browse Landscape

Phase

Phase 2 2Phase 4 1Phase 3 1Phase 1 1

Status

Completed 10Active not recruiting 10Recruiting 8Not yet recruiting 6Unknown 4Terminated 4Withdrawn 1No longer available 1Enrolling by invitation 1

Sponsor Class

OTHER 5INDUSTRY 1

Study Type

Interventional 5Observational 1

Sponsor

Cancer Type

Thoracic 6

Conditions

Carcinoma, Non-Small-Cell Lung 2Neoadjuvant Non-Small Cell Lung Cancer 1NSCLC 1Lung Neoplasms 1Adenocarcinoma of Lung 1ALK Positive Non-small Cell Lung Cancer 1

Interventions

Carboplatin 60Cisplatin 39Drug Therapy 37Pemetrexed 36osimertinib 22anlotinib 22Etoposide 19tislelizumab 17Surgical Procedures, Operative 16Paclitaxel 16Radiotherapy 15toripalimab 14130-nm albumin-bound paclitaxel 14pembrolizumab 13Docetaxel 13aflutinib 12Bevacizumab 12sintilimab 10Specimen Handling 10Magnetic Resonance Spectroscopy 9durvalumab 8cemiplimab 8Platinum 8Injections 8Immunotherapy 8Platinum Compounds 7PM 01183 7Blood Specimen Collection 7lorlatinib 6ensartinib 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Not yet recruiting × lorlatinib × Thoracic × Clear all
NCT07617337 2026-06-01

AQUA07 in Patients With ALK-Positive Non-Small Cell Lung Cancer

Chugai Pharmaceutical

Phase 1 Not yet recruiting
102 enrolled
Thoracic

ALK Positive Non-small Cell Lung Cancer

NCT07083687 2025-07-24

Lorlatinib in ROS1+ NSCLC With Brain Metastasis

Hunan Cancer Hospital

Phase 2 Not yet recruiting
21 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06893354 2025-03-25

Explore the Mechanisms Underlying Disease Resistance and Potential Primary Resistance Mechanism of Induction Therapy Lorlatinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harboring ALK Positive Mutation Revealed by Single-cell RNA Sequencing and Spatial Transcriptomics

The First Affiliated Hospital of Guangzhou Medical University

Phase 4 Not yet recruiting
20 enrolled
Thoracic

NSCLC

NCT06858410 2025-03-05

Lorlatinib Compared with Concurrent/ Sequential Chemoradiotherapy in Stage III ALK Positive Lung Adenocarcinoma

Guangdong Association of Clinical Trials

Phase 3 Not yet recruiting
36 enrolled
Thoracic

Adenocarcinoma of Lung

NCT06690541 2024-11-15

COMLORLA

Peking University Cancer Hospital & Institute

Not yet recruiting
100 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT06682884 2024-11-12

NEOLORA

Peking University People's Hospital

Phase 2 Not yet recruiting
25 enrolled
Thoracic

Neoadjuvant Non-Small Cell Lung Cancer

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