Clinical Trials

Other solid neoplasmThoracic

Small Cell Lung Carcinoma

NCT02863055 2025-09-19

NEMO

Phase 2 Terminated

37 enrolled

Mesothelioma, Malignant

NCT02299141 2025-06-24

Nintedanib in Molecularly Selected Patients With Advanced Non-Small Cell Lung Cancer

20 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung

NCT02496585 2025-04-16

Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis

34 enrolled 10 charts

Lung Neoplasms, Radiation Pneumonitis

NCT02231164 2025-02-13

LUME-Columbus: Nintedanib Plus Docetaxel in Advanced Non-small Cell Lung Cancer With Translational Research

Phase 3 Terminated

12 enrolled 7 charts

Carcinoma, Non-Small-Cell Lung

NCT01346540 2025-02-12

A Phase I/II Study of Continuous Oral Treatment With BIBF 1120 Added to Standard Gemcitabine/Cisplatin Therapy in First Line NSCLC Patients With Squamous Cell Histology.

16 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung

NCT02300298 2025-02-11

Nintedanib Plus Docetaxel in Japanese Patients With Adenocarcinoma Subtype Non-small Cell Lung Cancer After Failure of First Line Chemotherapy

10 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung

NCT06071013 2025-01-23

Nintedanib Plus EGFR TKI In EGFR-mutated Non-small Cell Lung Cancer Patients

Phase 1/2 Recruiting

20 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02225405 2024-05-08

Cisplatin, Docetaxel, and Nintedanib Before Surgery in Treating Patients With Previously Untreated Stage IB-IIIA Non-small Cell Lung Cancer

26 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02568449 2021-12-09

Nintedanib in Treating Patients With Malignant Pleural Mesothelioma That Is Recurrent

Other solid neoplasmThoracic

20 enrolled 11 charts

Mesothelioma, Malignant

NCT02531737 2021-08-10

REFRACT

59 enrolled

Lung Neoplasms

NCT02668393 2021-01-29

Nintedanib and Weekly Docetaxel in Lung Adenocarcinoma

14 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung

NCT03361319 2020-11-24

N3

Phase 1/2 Withdrawn

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Recurrence

NCT02452463 2020-04-06

Nintedanib Compared With Placebo in Treating Against Radiation-Induced Pneumonitis in Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery and Are Undergoing Chemoradiation Therapy

Phase 2 Terminated

8 enrolled 25 charts

Other solid neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Radiation Pneumonitis

NCT01907100 2019-03-18

Nintedanib (BIBF 1120) in Mesothelioma

Phase 2/3 Terminated

545 enrolled 15 charts

Mesothelioma

NCT02751385 2019-03-14

Investigation of the Effect of Nintedanib on the Pharmacokinetics of a Combination of Ethinylestradiol and Levonorgestrel in Patients With Non-small Cell Lung Cancer

Phase 1 Terminated

2 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung

NCT00805194 2018-12-05

LUME-Lung 1: BIBF 1120 Plus Docetaxel as Compared to Placebo Plus Docetaxel in 2nd Line Non Small Cell Lung Cancer

Phase 3 Completed

1,314 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT01441297 2017-08-25

BIBF 1120 as Second Line Treatment for Small Cell Lung Cancer

24 enrolled

Small Cell Lung Carcinoma

NCT01948141 2017-06-08

Nintedanib in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Failed Up to Two Previous Chemotherapy Regimens

6 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung

NCT00806819 2017-02-02

Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC

Phase 3 Completed

718 enrolled 21 charts

Carcinoma, Non-Small-Cell Lung

NCT02152059 2016-07-06

A Study to Evaluate the Good and Bad Effects of BIBF1120 in Small Cell Lung Cancer Patients Who Have Previously Benefited From First-line Platinum-based Chemotherapy

Phase 2 Withdrawn

Small Cell Lung Carcinoma

NCT01684111 2016-01-18

VENUS-1

7 enrolled

Carcinoma, Non-Small-Cell Lung

NCT01683682 2015-01-26

VENUS-2

8 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02182102 2014-07-18

Dose Escalation of BIBF 1120 Combined With Pemetrexed in Advanced Non Small Cell Lung Cancer

26 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02182232 2014-07-18

A Dose Escalation Study of BIBF 1120 Together With Paclitaxel and Carboplatin in Patients With Advanced Stage Non-small-cell Lung Cancer

33 enrolled